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@ARTICLE{Zitricky:278420,
author = {F. Zitricky and A. Försti$^*$ and A. Hemminki and K.
Hemminki$^*$},
title = {{C}onditional survival in breast cancer up to 10 years in
the {N}ordic countries.},
journal = {Cancer medicine},
volume = {12},
number = {17},
issn = {2045-7634},
address = {Hoboken, NJ},
publisher = {Wiley},
reportid = {DKFZ-2023-01654},
pages = {17945-17951},
year = {2023},
note = {#LA:C020# / 2023 Sep;12(17):17945-17951},
abstract = {Survival in breast cancer (BC) has developed favorably but
late recurrences are still a problem.We model survival data
from the NORDCAN database and analyze 1-, 5-, and 10-year
relative survival and 5/1- and 10/5-year conditional
survival in BC from Denmark (DK), Finland (FI), Norway (NO),
and Sweden (SE) between 1971 and 2020. Conditional survival
measures survival in those who had survived year 1 to reach
year 5 (5/1), or in those who had survived year 5 to reach
year 10 (10/5).Almost all survival metrics were best for SE
but survival in all countries improved in the course of time
approaching the SE levels which were $98.3\%$ for 1-year,
$92.3\%$ for 5-year, and $87.8\%$ for 10-year survival.
Conditional 10/5-year survival, covering 5 years, was better
than 5/1-year survival, covering 4 years. A contributing
factor is most likely the high rate of recurrence in period
2-5 years. The difference was observed for all countries but
for DK 10/5-year survival approached 1-year survival and for
NO and SE 10/5-year survival was only barely better than
5/1-year survival. The explanation to this was the excellent
10/5-year survival in DK compared to SE and particularly to
NO. Literature search suggested that the reason for the
relatively low 10/5-year survival in NO might be stagnant
survival development in old patients.We assume that late
mortality is critically limiting survival in BC and either
interference with the late metastatic process or effective
treatment will be key to future improvements in BC
survival.},
keywords = {conditional survival (Other) / metastasis (Other) /
periodic survival (Other) / recurrence (Other) / screening
(Other) / treatment (Other)},
cin = {B062 / HD01 / C020},
ddc = {610},
cid = {I:(DE-He78)B062-20160331 / I:(DE-He78)HD01-20160331 /
I:(DE-He78)C020-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:37578395},
doi = {10.1002/cam4.6436},
url = {https://inrepo02.dkfz.de/record/278420},
}