%0 Journal Article
%A Dettmer-Monaco, Viviane
%A Weißert, Kristoffer
%A Ammann, Sandra
%A Monaco, Gianni
%A Lei, Lei
%A Gräßel, Linda
%A Rhiel, Manuel
%A Rositzka, Julia
%A Kaufmann, Masako M
%A Geiger, Kerstin
%A Andrieux, Geoffroy
%A Lao, Jessica
%A Thoulass, Gudrun
%A Schell, Christoph
%A Börries, Melanie
%A Illert, Anna Lena
%A Cornu, Tatjana I
%A Ehl, Stephan
%A Aichele, Peter
%A Cathomen, Toni
%T Gene editing of hematopoietic stem cells restores T cell response in familial hemophagocytic lymphohistiocytosis.
%J The journal of allergy and clinical immunology
%V 153
%N 1
%@ 0091-6749
%C Amsterdam [u.a.]
%I Elsevier
%M DKFZ-2023-01687
%P 243-255.e14
%D 2024
%Z 2024 Jan;153(1):243-255.e14
%X Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory disorder characterized by a life-threatening cytokine storm and immunopathology. Familial HLH type 3 (FHL3) accounts for ∼30
%K CAST-Seq (Other)
%K CRISPR-Cas (Other)
%K T cell repertoire (Other)
%K autologous stem cell transplantation (Other)
%K gene therapy (Other)
%K genome editing (Other)
%K genotoxicity (Other)
%K hemophagocytic lymphohistiocytosis (Other)
%K hyperinflammation (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37595758
%R 10.1016/j.jaci.2023.08.003
%U https://inrepo02.dkfz.de/record/278643