%0 Journal Article
%A Heesen, Philip
%A Ranft, Andreas
%A Bhadri, Vivek
%A Brichard, Benedicte
%A Collaud, Stephane
%A Cyprova, Sona
%A Eich, Hans
%A Ek, Torben
%A Gelderblom, Hans
%A Hardes, Jendrik
%A Haveman, Lianne
%A Jabar, Susanne
%A Hartmann, Wolfgang
%A Andreou, Dimosthenis
%A Hauser, Peter
%A Kersting, Josephine
%A Juergens, Heribert
%A Kanerva, Jukka
%A Kühne, Thomas
%A Raciborska, Anna
%A Rascon, Jelena
%A Streitbürger, Arne
%A Timmermann, Beate
%A Uhlenbruch, Yasmin
%A Dirksen, Uta
%T Association between local treatment modalities and event-free survival, overall survival, and local recurrence in patients with localised Ewing Sarcoma. Report from the Ewing 2008 trial.
%J European journal of cancer
%V 192
%@ 0014-2964
%C Amsterdam [u.a.]
%I Elsevier
%M DKFZ-2023-01689
%P 113260
%D 2023
%X Local treatment is a crucial element in the standard of care for Ewing sarcoma (EWS). While systemic treatment is improved in randomised clinical trials, local treatment modalities are discussed controversially. We analysed the association between local therapy and event-free survival (EFS), overall survival (OS), and local recurrence (LR) in prospectively collected data of patients with localised EWS.We analysed data from the international Ewing 2008 study registered between 2009 and 2019 in 117 centres. After induction chemotherapy, patients received surgery, radiotherapy, or a combination thereof. We performed Cox regression, conducted propensity score-weighted sensitivity analysis, and performed subgroup analyses. Hazard ratios (HRs) and 95
%K Bone tumour (Other)
%K Ewing sarcoma (Other)
%K Local therapy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37595489
%R 10.1016/j.ejca.2023.113260
%U https://inrepo02.dkfz.de/record/278645