TY  - JOUR
AU  - Picard, Daniel
AU  - Felsberg, Jörg
AU  - Langini, Maike
AU  - Stachura, Paweł
AU  - Qin, Nan
AU  - Macas, Jadranka
AU  - Reiss, Yvonne
AU  - Bartl, Jasmin
AU  - Selt, Florian
AU  - Sigaud, Romain
AU  - Meyer, Frauke-D
AU  - Stefanski, Anja
AU  - Stühler, Kai
AU  - Roque, Lucia
AU  - Roque, Rafael
AU  - Pandyra, Aleksandra A
AU  - Brozou, Triantafyllia
AU  - Knobbe-Thomsen, Christiane
AU  - Plate, Karl H
AU  - Roesch, Alexander
AU  - Milde, Till
AU  - Reifenberger, Guido
AU  - Leprivier, Gabriel
AU  - Faria, Claudia C
AU  - Remke, Marc
TI  - Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma.
JO  - Acta neuropathologica
VL  - 146
IS  - 4
SN  - 0001-6322
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2023-01793
SP  - 551-564
PY  - 2023
N1  - 2023 Oct;146(4):551-564
AB  - Pilocytic astrocytoma (PA), the most common pediatric brain tumor, is driven by aberrant mitogen-activated protein kinase signaling most commonly caused by BRAF gene fusions or activating mutations. While 5-year overall survival rates exceed 95
KW  - Integrative multi-omics (Other)
KW  - Intertumoral heterogeneity (Other)
KW  - Pilocytic astrocytoma (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37656187
DO  - DOI:10.1007/s00401-023-02626-5
UR  - https://inrepo02.dkfz.de/record/282504
ER  -