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000282727 041__ $$aEnglish
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000282727 1001_ $$00000-0003-4139-1979$$aTichanek, Filip$$b0
000282727 245__ $$aLong-Term Periodic and Conditional Survival Trends in Prostate, Testicular, and Penile Cancers in the Nordic Countries, Marking Timing of Improvements.
000282727 260__ $$aBasel$$bMDPI$$c2023
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000282727 520__ $$aSurvival studies are important tools for cancer control, but long-term survival data on high-quality cancer registries are lacking for all cancers, including prostate (PC), testicular (TC), and penile cancers. Using generalized additive models and data from the NORDCAN database, we analyzed 1- and 5-year relative survival for these cancers in Denmark (DK), Finland (FI), Norway (NO), and Sweden (SE) over a 50-year period (1971-2020). We additionally estimated conditional 5/1-year survival for patients who survived the 1st year after diagnosis. Survival improved early for TC, and 5-year survival reached 90% between 1985 (SE) and 2000 (FI). Towards the end of the follow-up, the TC patients who had survived the 1st year survived the next 4 years with comparable probability to the background population. For PC, the 90% landmark was reached between 2000 (FI) and after 2010 (DK). For penile cancer, 5-year survival never reached the 90% landmark, and the improvements in survival were modest at best. For TC, early mortality requires attention, whereas late mortality should be tackled for PC. For penile cancer, the relatively high early mortality may suggest delays in diagnosis and would require more public awareness and encouragement of patients to seek medical opinion. In FI, TC and penile cancer patients showed roughly double risk of dying compared to the other Nordic countries, which warrants further study and clinical attention.
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000282727 650_7 $$2Other$$aconditional survival
000282727 650_7 $$2Other$$aperiodic survival
000282727 650_7 $$2Other$$aprognosis
000282727 650_7 $$2Other$$atime trends
000282727 650_7 $$2Other$$atreatment
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000282727 7001_ $$00000-0001-7103-8530$$aHemminki, Akseli$$b2
000282727 7001_ $$00000-0002-3396-2391$$aHemminki, Otto$$b3
000282727 7001_ $$0P:(DE-He78)19b0ec1cea271419d9fa8680e6ed6865$$aHemminki, Kari$$b4$$eLast author$$udkfz
000282727 773__ $$0PERI:(DE-600)2527080-1$$a10.3390/cancers15174261$$gVol. 15, no. 17, p. 4261 -$$n17$$p4261$$tCancers$$v15$$x2072-6694$$y2023
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