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@ARTICLE{Witte:282752,
author = {M.-L. Witte and A. Schoneberg and S. Hanss and M.
Lablans$^*$ and J. Vehreschild and D. Krefting},
title = {{A}daptability of {E}xisting {F}easibility {T}ools for
{C}linical {S}tudy {R}esearch {D}ata {P}latforms.},
journal = {Studies in health technology and informatics},
volume = {307},
issn = {0926-9630},
address = {Amsterdam},
publisher = {IOS Press},
reportid = {DKFZ-2023-01871},
isbn = {9781643684284 (print)},
pages = {39-48},
year = {2023},
abstract = {The increasing need for secondary use of clinical study
data requires FAIR infrastructures, i.e. provide findable,
accessible, interoperable and reusable data. It is crucial
for data scientists to assess the number and distribution of
cohorts that meet complex combinations of criteria defined
by the research question. This so-called feasibility test is
increasingly offered as a self-service, where scientists can
filter the available data according to specific parameters.
Early feasibility tools have been developed for biosamples
or image collections. They are of high interest for clinical
study platforms that federate multiple studies and data
types, but they pose specific requirements on the
integration of data sources and data protection.Mandatory
and desired requirements for such tools were acquired from
two user groups - primary users and staff managing a
platform's transfer office. Open Source feasibility tools
were sought by different literature search strategies and
evaluated on their adaptability to the requirements.We
identified seven feasibility tools that we evaluated based
on six mandatory properties.We determined five feasibility
tools to be most promising candidates for adaption to a
clinical study research data platform, the Clinical
Communication Platform, the German Portal for Medical
Research Data, the Feasibility Explorer, Medical
Controlling, and the Sample Locator.},
keywords = {Humans / Feasibility Studies / Biomedical Research /
Physicians / FAIR (Other) / clinical study (Other) / data
provision (Other) / data reuse (Other) / feasibility (Other)
/ findability (Other) / software tools (Other) / user
interface (Other)},
cin = {E260},
ddc = {300},
cid = {I:(DE-He78)E260-20160331},
pnm = {315 - Bildgebung und Radioonkologie (POF4-315)},
pid = {G:(DE-HGF)POF4-315},
typ = {PUB:(DE-HGF)3 / PUB:(DE-HGF)16},
pubmed = {pmid:37697836},
doi = {DOI: 10.3233/SHTI230691},
url = {https://inrepo02.dkfz.de/record/282752},
}