%0 Journal Article
%A Jaikuna, Tanwiwat
%A Osorio, Eliana Vasquez
%A Azria, David
%A Chang-Claude, Jenny
%A De Santis, Maria Carmen
%A Gutiérrez-Enríquez, Sara
%A van Herk, Marcel
%A Hoskin, Peter
%A Lambrecht, Maarten
%A Lingard, Zoe
%A Seibold, Petra
%A Seoane, Alejandro
%A Sperk, Elena
%A Symonds, R Paul
%A Talbot, Christopher J
%A Rancati, Tiziana
%A Rattay, Tim
%A Reyes, Victoria
%A Rosenstein, Barry S
%A de Ruysscher, Dirk
%A Vega, Ana
%A Veldeman, Liv
%A Webb, Adam
%A West, Catharine M L
%A Aznar, Marianne C
%T Contouring variation affects estimates of normal tissue complication probability for breast fibrosis after radiotherapy.
%J The breast
%V 72
%@ 0960-9776
%C Amsterdam [u.a.]
%I Elsevier
%M DKFZ-2023-01891
%P 103578
%D 2023
%X Normal tissue complication probability (NTCP) models can be useful to estimate the risk of fibrosis after breast-conserving surgery (BCS) and radiotherapy (RT) to the breast. However, they are subject to uncertainties. We present the impact of contouring variation on the prediction of fibrosis.280 breast cancer patients treated BCS-RT were included. Nine Clinical Target Volume (CTV) contours were created for each patient: i) CTV_crop (reference), cropped 5 mm from the skin and ii) CTV_skin, uncropped and including the skin, iii) segmenting the 95
%K Breast cancer (Other)
%K Fibrosis (Other)
%K Inter-observer variation (Other)
%K Late effects (Other)
%K NTCP modelling (Other)
%K Radiotherapy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37713940
%R 10.1016/j.breast.2023.103578
%U https://inrepo02.dkfz.de/record/282898