TY  - JOUR
AU  - Jaikuna, Tanwiwat
AU  - Osorio, Eliana Vasquez
AU  - Azria, David
AU  - Chang-Claude, Jenny
AU  - De Santis, Maria Carmen
AU  - Gutiérrez-Enríquez, Sara
AU  - van Herk, Marcel
AU  - Hoskin, Peter
AU  - Lambrecht, Maarten
AU  - Lingard, Zoe
AU  - Seibold, Petra
AU  - Seoane, Alejandro
AU  - Sperk, Elena
AU  - Symonds, R Paul
AU  - Talbot, Christopher J
AU  - Rancati, Tiziana
AU  - Rattay, Tim
AU  - Reyes, Victoria
AU  - Rosenstein, Barry S
AU  - de Ruysscher, Dirk
AU  - Vega, Ana
AU  - Veldeman, Liv
AU  - Webb, Adam
AU  - West, Catharine M L
AU  - Aznar, Marianne C
TI  - Contouring variation affects estimates of normal tissue complication probability for breast fibrosis after radiotherapy.
JO  - The breast
VL  - 72
SN  - 0960-9776
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DKFZ-2023-01891
SP  - 103578
PY  - 2023
AB  - Normal tissue complication probability (NTCP) models can be useful to estimate the risk of fibrosis after breast-conserving surgery (BCS) and radiotherapy (RT) to the breast. However, they are subject to uncertainties. We present the impact of contouring variation on the prediction of fibrosis.280 breast cancer patients treated BCS-RT were included. Nine Clinical Target Volume (CTV) contours were created for each patient: i) CTV_crop (reference), cropped 5 mm from the skin and ii) CTV_skin, uncropped and including the skin, iii) segmenting the 95
KW  - Breast cancer (Other)
KW  - Fibrosis (Other)
KW  - Inter-observer variation (Other)
KW  - Late effects (Other)
KW  - NTCP modelling (Other)
KW  - Radiotherapy (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37713940
DO  - DOI:10.1016/j.breast.2023.103578
UR  - https://inrepo02.dkfz.de/record/282898
ER  -