%0 Journal Article
%A Kersting, David
%A Moraitis, Alexandros
%A Sraieb, Miriam
%A Zarrad, Fadi
%A Umutlu, Lale
%A Rischpler, Christoph
%A Peter Fendler, Wolfgang
%A Herrmann, Ken
%A Weber, Manuel
%A Conti, Maurizio
%A Fragoso Costa, Pedro
%A Jentzen, Walter
%T Quantification performance of silicon photomultiplier-based PET for small 18F-, 68Ga- and 124I-avid lesions in the context of radionuclide therapy planning.
%J Physica medica
%V 114
%@ 1120-1797
%C Amsterdam
%I Elsevier
%M DKFZ-2023-01979
%P 103149
%D 2023
%Z 2023 Oct:114:103149
%X The aim of this study was to investigate conditions for reliable quantification of sub-centimeter lesions with low18F,68Ga, and124I uptake using a silicon photomultiplier-based PET/CT system.A small tumor phantom was investigated under challenging but clinically realistic conditions resembling prostate and thyroid cancer lymph node metastases (6 spheres with 3.7-9.7 mm in diameter, 9 different activity concentrations ranging from about 0.25-25 kBq/mL, and a signal-to-background ratio of 20). Radionuclides with different positron branching ratios and prompt gamma coincidence contributions were investigated. Maximum-, contour-, and oversize-based partial volume effect (PVE) correction approaches were applied. Detection and quantification performance were estimated, considering a ±30 
%K Digital PET/CT (Other)
%K Dosimetry (Other)
%K Radionuclide Therapy Planning (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37778973
%R 10.1016/j.ejmp.2023.103149
%U https://inrepo02.dkfz.de/record/284385