%0 Journal Article
%A Liebers, Nora
%A Bruch, Peter-Martin
%A Terzer, Tobias
%A Hernandez-Hernandez, Miguel
%A Paramasivam, Nagarajan
%A Fitzgerald, Donnacha
%A Altmann, Heidi
%A Roider, Tobias
%A Kolb, Carolin
%A Knoll, Mareike
%A Lenze, Angela
%A Platzbecker, Uwe
%A Röllig, Christoph
%A Baldus, Claudia
%A Serve, Hubert
%A Bornhäuser, Martin
%A Hübschmann, Daniel
%A Müller-Tidow, Carsten
%A Stölzel, Friedrich
%A Huber, Wolfgang
%A Benner, Axel
%A Zenz, Thorsten
%A Lu, Junyan
%A Dietrich, Sascha
%T Ex vivo drug response profiling for response and outcome prediction in hematologic malignancies: the prospective non-interventional SMARTrial.
%J Nature cancer
%V 4
%N 12
%@ 2662-1347
%C London
%I Nature Research
%M DKFZ-2023-01992
%P 1648-1659
%D 2023
%Z 2023 Dec;4(12):1648-1659 / #EA:B340#LA:B340#
%X Ex vivo drug response profiling is a powerful tool to study genotype-drug response associations and is being explored as a tool set for precision medicine in cancer. Here we conducted a prospective non-interventional trial to investigate feasibility of ex vivo drug response profiling for treatment guidance in hematologic malignancies (SMARTrial, NCT03488641 ). The primary endpoint to provide drug response profiling reports within 7 d was met in 91
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37783805
%R 10.1038/s43018-023-00645-5
%U https://inrepo02.dkfz.de/record/284403