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@ARTICLE{Zhao:284937,
author = {B. Zhao$^*$ and M. Kilian$^*$ and T. Bunse$^*$ and M.
Platten$^*$ and L. Bunse$^*$},
title = {{T}umor-reactive {T} helper cells in the context of
vaccination against glioma.},
journal = {Cancer cell},
volume = {41},
number = {11},
issn = {1535-6108},
address = {New York, NY},
publisher = {Elsevier},
reportid = {DKFZ-2023-02137},
pages = {1829-1834},
year = {2023},
note = {#EA:D170#LA:D170# / 2023 Nov 13;41(11):1829-1834 / HI-TRON
/ review email KST},
abstract = {With the advances in immunogenomics, the majority of
tumor-specific antigens were found to be recognized by T
helper cells (THCs). This observation led to the development
of long epitope vaccines in various cancers.
Mechanistically, we are still gaining a deeper understanding
of the mode of action of THCs as precision antitumor
agonists. Here, we discuss the specific cellular mechanisms
of THC functions in glioma immunology and contextualize
current advances in anti-glioma vaccination exploiting
THCs.},
subtyp = {Review Article},
cin = {D170 / HD01},
ddc = {610},
cid = {I:(DE-He78)D170-20160331 / I:(DE-He78)HD01-20160331},
pnm = {314 - Immunologie und Krebs (POF4-314)},
pid = {G:(DE-HGF)POF4-314},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:37863064},
doi = {10.1016/j.ccell.2023.09.013},
url = {https://inrepo02.dkfz.de/record/284937},
}