%0 Journal Article
%A Vogel, Jonas
%A Seith, Ferdinand
%A Estler, Arne
%A Nikolaou, Konstantin
%A Schmidt, Holger
%A la Fougère, Christian
%A Küstner, Thomas
%T Impact of Tracer Dose Reduction in [18 F]-Labelled Fluorodeoxyglucose-Positron Emission Tomography ([18 F]-FDG)-PET) on Texture Features and Histogram Indices: A Study in Homogeneous Tissues of Phantom and Patient.
%J Tomography
%V 9
%N 5
%@ 2379-1381
%C Ann Arbor, Michigan
%I Grapho Publications
%M DKFZ-2023-02188
%P 1799 - 1810
%D 2023
%X Histogram indices (HIs) and texture features (TFs) are considered to play an important role in future oncologic PET-imaging and it is unknown how these indices are affected by changes of tracer doses. A randomized undersampling of PET list mode data enables a simulation of tracer dose reduction. We performed a phantom study to compare HIs/TFs of simulated and measured tracer dose reductions and evaluated changes of HIs/TFs in the liver of patients with PETs from simulated reduced tracer doses. Overall, 42 HIs/TFs were evaluated in a NEMA phantom at measured and simulated doses (stepwise reduction of [18 F] from 100
%K Humans
%K Fluorodeoxyglucose F18
%K Drug Tapering
%K Positron-Emission Tomography: methods
%K Radiopharmaceuticals
%K Neoplasms: diagnostic imaging
%K Neoplasms: radiotherapy
%K FDG (Other)
%K PET (Other)
%K dose reduction (Other)
%K radiomics (Other)
%K texture features (Other)
%K Fluorodeoxyglucose F18 (NLM Chemicals)
%K Radiopharmaceuticals (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37888735
%2 pmc:PMC10611106
%R 10.3390/tomography9050143
%U https://inrepo02.dkfz.de/record/285045