TY  - JOUR
AU  - Roohani, Siyer
AU  - Claßen, Noa Marie
AU  - Ehret, Felix
AU  - Jarosch, Armin
AU  - Dziodzio, Tomasz
AU  - Flörcken, Anne
AU  - Märdian, Sven
AU  - Zips, Daniel
AU  - Kaul, David
TI  - The role of radiotherapy in the management of malignant peripheral nerve sheath tumors: a single-center retrospective cohort study.
JO  - Journal of cancer research and clinical oncology
VL  - 149
IS  - 20
SN  - 0301-1585
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2023-02272
SP  - 17739-17747
PY  - 2023
N1  - 2023 Dec;149(20):17739-17747
AB  - This study sought to investigate the role of radiotherapy (RT) in addition to surgery for oncological outcomes in patients with malignant peripheral nerve sheath tumors (MPNST).In this single-center, retrospective cohort study, histopathologically confirmed MPNST were analyzed. Local control (LC), overall survival (OS), and distant metastasis-free survival (DMFS) were assessed using the Kaplan-Meier estimator. Multivariable Cox regression analysis was performed to identify factors associated with LC, OS, and DMFS.We included 57 patients with a median follow-up of 20.0 months. Most MPNSTs were located deeply (87.5
KW  - Local control (Other)
KW  - MPNST (Other)
KW  - Malignant peripheral nerve sheath tumor (Other)
KW  - Prognostic factor (Other)
KW  - Radiotherapy (Other)
KW  - Survival (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37924493
DO  - DOI:10.1007/s00432-023-05449-9
UR  - https://inrepo02.dkfz.de/record/285237
ER  -