%0 Journal Article
%A Rauch, Julian
%A Laun, Frederik B
%A Bachert, Peter
%A Ladd, Mark E
%A Kuder, Tristan Anselm
%T Compensation of concomitant field effects in double diffusion encoding by means of added oscillating gradients.
%J Magnetic resonance imaging
%V 105
%@ 0730-725X
%C Amsterdam [u.a.]
%I Elsevier Science
%M DKFZ-2023-02309
%P 133-141
%D 2024
%Z #EA:E020#LA:E020# / 2024 Jan;105:133-141
%X Maxwell or concomitant fields imprint additional phases on the transverse magnetization. This concomitant phase may cause severe image artifacts like signal voids or distort the quantitative parameters due to the induced intravoxel dephasing. In particular, double diffusion encoding (DDE) schemes with two pairs of bipolar diffusion weighting gradients separated by a refocusing radiofrequency (RF) pulse are prone to concomitant field-induced artifacts. In this work, a method for reducing concomitant field effects in these DDE sequences based on additional oscillating gradients is presented. These oscillating gradient pulses obtained by constrained optimization were added to the original gradient waveforms. The modified sequences reduced the accumulated concomitant phase without significant changes in the original sequence characteristics. The proposed method was applied to a DDE acquisition scheme consisting of 60 pairs of diffusion wave vectors. For phantom as well as for in vivo experiments, a considerable increase in the signal-to-noise ratio (SNR) was obtained. For phantom measurements with a diffusion weighting of b = 2000 s/mm2 for each of the gradient pairs, an SNR increase of up to 40
%K Concomitant fields (Other)
%K Diffusion weighting (Other)
%K Double diffusion encoding (Other)
%K Optimization (Other)
%K Oscillating gradients (Other)
%K Sequence design (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37939973
%R 10.1016/j.mri.2023.11.006
%U https://inrepo02.dkfz.de/record/285284