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@ARTICLE{Schunn:285359,
      author       = {F. A. Schunn and R. A. El Shafie and D. Kronsteiner and L.
                      D. Sauer and A. Kudak and N. Bougatf and D. Oetzel and A.
                      Krämer and S. Regnery and T. Machmer and J. Debus$^*$ and
                      N. H. Nicolay$^*$},
      title        = {{O}ncologic treatment support via a dedicated mobile app: a
                      prospective feasibility evaluation ({OPTIMISE}-1).},
      journal      = {Strahlentherapie und Onkologie},
      volume       = {200},
      number       = {6},
      issn         = {0179-7158},
      address      = {Heidelberg},
      publisher    = {Springer Medizin},
      reportid     = {DKFZ-2023-02328},
      pages        = {475-486},
      year         = {2024},
      note         = {2024 Jun;200(6):475-486 / #LA:E055#},
      abstract     = {Mobile health (mhealth) is gaining interest, with mobile
                      devices and apps being ever more available among medical
                      facilities and patients. However, in the field of radiation
                      oncology, the medical benefits of mhealth apps are still
                      underexplored. As an additional approach to patient care
                      during radiotherapy, we designed a mobile treatment
                      surveillance app based on patient-reported outcomes.We aimed
                      to examine the feasibility of app-based treatment
                      surveillance in patients undergoing radiotherapy (RT).
                      Alongside technical practicability and acceptance, we
                      assessed patient satisfaction and quality of life during
                      treatment.This prospective single-center study was performed
                      at Heidelberg University Hospital between August 2018 and
                      January 2020. During RT we measured patients' quality of
                      life, symptoms, and treatment satisfaction. Respective
                      questionnaires (EORTC QLQ-C30 with diagnosis-specific
                      modules, RAND PSQ-18) were presented to patients via a
                      mobile app running on a designated tablet device. The
                      primary endpoint was determined by the fraction of patients
                      who completed at least $80\%$ of the items. Secondary
                      endpoints were disease-related quality of life and patient
                      satisfaction.A total of 49 cancer patients (14 breast, 13
                      pelvic, 12 lung, 10 prostate) were eligible for analysis.
                      $79.6\%$ $(95\%$ confidence interval: $66.4-88.5\%;$ n = 39)
                      of all patients completed at least $80\%$ of the items
                      received by the mobile app. A mean of 227.5 ± 48.25
                      questions were answered per patient. Breast cancer patients
                      showed the highest rate of answered questions, with $92.9\%$
                      (n = 13) completing at least $80\%$ of the items.Patients
                      showed high acceptance, with $79.6\%$ (n = 39) completing at
                      least $80\%$ of the given items. The use of a mobile app for
                      reporting symptoms and quality of life during RT is feasible
                      and well accepted by patients. It may allow for
                      resource-efficient, detailed feedback to the medical staff
                      and assist in the assessment of side effects over time.},
      keywords     = {Cancer (Other) / Patient-reported outcome measures (Other)
                      / Quality of life (Other) / Radiotherapy (Other) / mhealth
                      (Other)},
      cin          = {E050 / FR01 / E055},
      ddc          = {610},
      cid          = {I:(DE-He78)E050-20160331 / I:(DE-He78)FR01-20160331 /
                      I:(DE-He78)E055-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:37947806},
      doi          = {10.1007/s00066-023-02166-7},
      url          = {https://inrepo02.dkfz.de/record/285359},
}