%0 Journal Article %A Moen, Christian A %A Falkenthal, Thea E %A Thorkelsen, Tor K %A Hopland, Andreas %A Rio, Oline E %A Honoré, Alfred %A Juliebø-Jones, Patrick %A Dongre, Harsh N %A Costea, Daniela E %A Bostad, Leif %A Brennan, Paul %A Johansson, Mattias %A Ferreiro-Iglesias, Aida %A Brenner, Nicole %A Waterboer, Tim %A Nygård, Mari %A Beisland, Christian %T Penile Cancers Attributed to Human Papillomavirus Are Associated with Improved Survival for Node-positive Patients. Findings from a Norwegian Cohort Study Spanning 50 Years. %J European urology oncology %V 7 %N 4 %@ 2588-9311 %C Amsterdam %I Elsevier %M DKFZ-2023-02340 %P 778-785 %D 2024 %Z 2024 Aug;7(4):778-785 %X Human papillomavirus (HPV) infection is a risk factor for the development of penile squamous cell carcinoma (PSCC). It remains inconclusive whether HPV-related PSCC has a different prognosis from non-HPV-related PSCC.To investigate the relationship between HPV status and survival as well as temporal changes in the proportion of HPV-related PSCC.A retrospective cohort of 277 patients treated in Norway between 1973 and 2022 was investigated for HPV DNA in tumor tissue. Clinicopathological variables and disease course were registered.Kaplan-Meier curves and Cox regression were used to investigate the determinants of cancer-specific survival (CSS). The chi-square test for trend in proportions enabled investigation of temporal changes in the HPV-related proportion of PSCC patients treated in Western Norway (n = 211).HPV DNA was detected in tumor tissue from 131 (47 %K Cancer-specific survival (Other) %K Human papillomavirus (Other) %K Net survival (Other) %K Penile cancer (Other) %K Penile squamous cell carcinoma (Other) %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:37949729 %R 10.1016/j.euo.2023.10.013 %U https://inrepo02.dkfz.de/record/285371