Patent

DKFZ-2023-02441

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Compounds for preventing migration of cancer cells

Seco, J.DKFZ* ; Guerreiro, J. F. ; Gomes, M. ; Horn, A. ; Horn, C. F. ; Pagliari, F.DKFZ*

2022

Patent No.: US20220401402A1; 17766128

Abstract: The present invention relates to a composition for use in preventing migration of cancer cells in a subject known or suspected to suffer from cancer, the composition comprising at least one metal complex having the structure (I), formula (I), wherein M is a metal, preferably selected from the group consisting of copper, iron, manganese and zinc, X is Xa or Xb, wherein Xa is selected from the group consisting of O, S and—N (R1)—, wherein R1 is H or alkyl, and wherein Xb is a group forming a coordinate covalent bond to a second metal M′, preferably a group O, S or—N (R1)—, wherein M′ is preferably selected from the group consisting of copper, iron, manganese and zinc, and wherein M′ and M may be the same or different and are preferably the same, Z1 and Z2 are independently of each other a, substituted or unsubstituted,-Aryl-O—,-Aryl-N—or heteroaryl group, Y is Ya or Yb, wherein Ya is selected from the …

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Contributing Institute(s):

1. E041 Med. Physik in der Radioonkologie (E041)

Research Program(s):

1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2022

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