%0 Journal Article
%A Heiss, Rafael
%A Weber, Marc-André
%A Balbach, Eva L
%A Hinsen, Maximilian
%A Geissler, Frederik
%A Nagel, Armin M
%A Ladd, Mark E
%A Arkudas, Andreas
%A Horch, Raymund E
%A Gall, Christine
%A Uder, Michael
%A Roemer, Frank W
%T Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI.
%J European radiology experimental
%V 7
%N 1
%@ 2509-9280
%C [Cham]
%I Springer International Publishing
%M DKFZ-2023-02717
%P 80
%D 2023
%X To analyze regional variations in T2 and T2* relaxation times in wrist joint cartilage and the triangular fibrocartilage complex (TFCC) at 3 and 7 T and to compare values between field strengths.Twenty-five healthy controls and 25 patients with chronic wrist pain were examined at 3 and 7 T on the same day using T2- and T2*-weighted sequences. Six different regions of interest (ROIs) were evaluated for cartilage and 3 ROIs were evaluated at the TFCC based on manual segmentation. Paired t-tests were used to compare T2 and T2* values between field strengths and between different ROIs. Spearman's rank correlation was calculated to assess correlations between T2 and T2* time values at 3 and 7 T.T2 and T2* time values of the cartilage differed significantly between 3 and 7 T for all ROIs (p ≤ 0.045), with one exception: at the distal lunate, no significant differences in T2 values were observed between field strengths. T2* values differed significantly between 3 and 7 T for all ROIs of the TFCC (p ≤ 0.001). Spearman's rank correlation between 3 and 7 T ranged from 0.03 to 0.62 for T2 values and from 0.01 to 0.48 for T2* values. T2 and T2* values for cartilage varied across anatomic locations in healthy controls at both 3 and 7 T.Quantitative results of T2 and T2* mapping at the wrist differ between field strengths, with poor correlation between 3 and 7 T. Local variations in cartilage T2 and T2* values are observed in healthy individuals.T2 and T2* mapping are feasible for compositional imaging of the TFCC and the cartilage at the wrist at both 3 and 7 T, but the clinical interpretation remains challenging due to differences between field strengths and variations between anatomic locations.•Field strength and anatomic locations influence T2 and T2* values at the wrist. •T2 and T2* values have a poor correlation between 3 and 7 T. •Local reference values are needed for each anatomic location for reliable interpretation.
%K Cartilage (articular) (Other)
%K Image processing (computer-assisted) (Other)
%K Magnetic resonance imaging (Other)
%K Triangular fibrocartilage (Other)
%K Wrist joint (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38093075
%R 10.1186/s41747-023-00394-1
%U https://inrepo02.dkfz.de/record/286213