TY  - JOUR
AU  - Heiss, Rafael
AU  - Weber, Marc-André
AU  - Balbach, Eva L
AU  - Hinsen, Maximilian
AU  - Geissler, Frederik
AU  - Nagel, Armin M
AU  - Ladd, Mark E
AU  - Arkudas, Andreas
AU  - Horch, Raymund E
AU  - Gall, Christine
AU  - Uder, Michael
AU  - Roemer, Frank W
TI  - Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI.
JO  - European radiology experimental
VL  - 7
IS  - 1
SN  - 2509-9280
CY  - [Cham]
PB  - Springer International Publishing
M1  - DKFZ-2023-02717
SP  - 80
PY  - 2023
AB  - To analyze regional variations in T2 and T2* relaxation times in wrist joint cartilage and the triangular fibrocartilage complex (TFCC) at 3 and 7 T and to compare values between field strengths.Twenty-five healthy controls and 25 patients with chronic wrist pain were examined at 3 and 7 T on the same day using T2- and T2*-weighted sequences. Six different regions of interest (ROIs) were evaluated for cartilage and 3 ROIs were evaluated at the TFCC based on manual segmentation. Paired t-tests were used to compare T2 and T2* values between field strengths and between different ROIs. Spearman's rank correlation was calculated to assess correlations between T2 and T2* time values at 3 and 7 T.T2 and T2* time values of the cartilage differed significantly between 3 and 7 T for all ROIs (p ≤ 0.045), with one exception: at the distal lunate, no significant differences in T2 values were observed between field strengths. T2* values differed significantly between 3 and 7 T for all ROIs of the TFCC (p ≤ 0.001). Spearman's rank correlation between 3 and 7 T ranged from 0.03 to 0.62 for T2 values and from 0.01 to 0.48 for T2* values. T2 and T2* values for cartilage varied across anatomic locations in healthy controls at both 3 and 7 T.Quantitative results of T2 and T2* mapping at the wrist differ between field strengths, with poor correlation between 3 and 7 T. Local variations in cartilage T2 and T2* values are observed in healthy individuals.T2 and T2* mapping are feasible for compositional imaging of the TFCC and the cartilage at the wrist at both 3 and 7 T, but the clinical interpretation remains challenging due to differences between field strengths and variations between anatomic locations.•Field strength and anatomic locations influence T2 and T2* values at the wrist. •T2 and T2* values have a poor correlation between 3 and 7 T. •Local reference values are needed for each anatomic location for reliable interpretation.
KW  - Cartilage (articular) (Other)
KW  - Image processing (computer-assisted) (Other)
KW  - Magnetic resonance imaging (Other)
KW  - Triangular fibrocartilage (Other)
KW  - Wrist joint (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:38093075
DO  - DOI:10.1186/s41747-023-00394-1
UR  - https://inrepo02.dkfz.de/record/286213
ER  -