Home > Publications database > Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI. > print

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024 7 _ |a 10.1186/s41747-023-00394-1
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041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Heiss, Rafael
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245 _ _ |a Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI.
260 _ _ |a [Cham]
|c 2023
|b Springer International Publishing
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520 _ _ |a To analyze regional variations in T2 and T2* relaxation times in wrist joint cartilage and the triangular fibrocartilage complex (TFCC) at 3 and 7 T and to compare values between field strengths.Twenty-five healthy controls and 25 patients with chronic wrist pain were examined at 3 and 7 T on the same day using T2- and T2*-weighted sequences. Six different regions of interest (ROIs) were evaluated for cartilage and 3 ROIs were evaluated at the TFCC based on manual segmentation. Paired t-tests were used to compare T2 and T2* values between field strengths and between different ROIs. Spearman's rank correlation was calculated to assess correlations between T2 and T2* time values at 3 and 7 T.T2 and T2* time values of the cartilage differed significantly between 3 and 7 T for all ROIs (p ≤ 0.045), with one exception: at the distal lunate, no significant differences in T2 values were observed between field strengths. T2* values differed significantly between 3 and 7 T for all ROIs of the TFCC (p ≤ 0.001). Spearman's rank correlation between 3 and 7 T ranged from 0.03 to 0.62 for T2 values and from 0.01 to 0.48 for T2* values. T2 and T2* values for cartilage varied across anatomic locations in healthy controls at both 3 and 7 T.Quantitative results of T2 and T2* mapping at the wrist differ between field strengths, with poor correlation between 3 and 7 T. Local variations in cartilage T2 and T2* values are observed in healthy individuals.T2 and T2* mapping are feasible for compositional imaging of the TFCC and the cartilage at the wrist at both 3 and 7 T, but the clinical interpretation remains challenging due to differences between field strengths and variations between anatomic locations.•Field strength and anatomic locations influence T2 and T2* values at the wrist. •T2 and T2* values have a poor correlation between 3 and 7 T. •Local reference values are needed for each anatomic location for reliable interpretation.
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650 _ 7 |a Cartilage (articular)
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650 _ 7 |a Image processing (computer-assisted)
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650 _ 7 |a Magnetic resonance imaging
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650 _ 7 |a Triangular fibrocartilage
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650 _ 7 |a Wrist joint
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700 1 _ |a Weber, Marc-André
|b 1
700 1 _ |a Balbach, Eva L
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700 1 _ |a Hinsen, Maximilian
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700 1 _ |a Geissler, Frederik
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700 1 _ |a Nagel, Armin M
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700 1 _ |a Ladd, Mark E
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700 1 _ |a Arkudas, Andreas
|b 7
700 1 _ |a Horch, Raymund E
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700 1 _ |a Gall, Christine
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700 1 _ |a Uder, Michael
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700 1 _ |a Roemer, Frank W
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773 _ _ |a 10.1186/s41747-023-00394-1
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