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@ARTICLE{Goldschmidt:286662,
author = {S. Goldschmidt$^*$ and M. Schmidt$^*$ and F. Rosenberger
and J. Wiskemann and K. Steindorf$^*$},
title = {{P}atterns and influencing factors of exercise attendance
of breast cancer patients during neoadjuvant chemotherapy.},
journal = {Supportive care in cancer},
volume = {32},
number = {1},
issn = {0941-4355},
address = {New York,NY},
publisher = {Springer},
reportid = {DKFZ-2024-00026},
pages = {79},
year = {2024},
note = {#EA:C110#LA:C110#},
abstract = {Performing 2-3 exercise sessions/week may relieve
therapy-related side effects of breast cancer patients
(BRCA) and improve their quality of life. However,
attendance to the exercise sessions is often impaired. Thus,
we investigated patterns and possible influencing factors of
attendance to an aerobic (AT) or resistance training (RT)
intervention in BRCA during neoadjuvant chemotherapy.BRCA (N
= 122) were randomly allocated to supervised AT or RT twice
weekly during neoadjuvant chemotherapy (18 ± 4 weeks).
Attendance was calculated individually and group-wise per
training week as the percentage of the performed sessions
out of the prescribed sessions. Possible influencing factors
were investigated using multiple regression analyses.Mean
individual attendance was $44.1\%$ ± $29.3\%$ with no
significant differences between the groups. Group-wise
attendance was highest in the first 6 weeks of training with
≥ $60\%$ for AT and ≥ $50\%$ for RT, but decreased over
the course of the intervention accompanying chemotherapy.
Significantly higher attendance was associated with not
having vs. having nausea (ß = - 14.57; p = 0.007) and not
having vs. having pain (ß = - 12.07; p = 0.12), whereas
fatigue did not show any association (ß = - 0.006; p =
0.96). Having been randomized into a preferred intervention
group $(48.8\%)$ showed no association with attendance. Yet,
patients' rating of the exercise intervention as 'good'/
'very good' $(58.7\%)$ was significantly associated with
higher attendance (p = 0.01).For both exercise
interventions, group-wise attendance/training week decreased
during chemotherapy despite good intervention ratings. While
some patients never started, others trained almost
constantly twice weekly. The study revealed that patients
who are nauseous or experience pain may need more support to
attend more exercise sessions. Trial Registration
Clinicaltrials.gov: NCT02999074 from May 6, 2016.},
keywords = {Attendance (Other) / Breast neoplasms (Other) / Exercise
intervention (Other) / Neoadjuvant chemotherapy (Other)},
cin = {C110},
ddc = {610},
cid = {I:(DE-He78)C110-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:38170301},
doi = {10.1007/s00520-023-08269-2},
url = {https://inrepo02.dkfz.de/record/286662},
}