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000287295 1001_ $$0P:(DE-He78)38900a0e1ae96a725db546cb7b909adb$$aVogel, Felix Christian Eduard$$b0$$eFirst author$$udkfz
000287295 245__ $$aLipids as mediators of cancer progression and metastasis.
000287295 260__ $$aLondon$$bNature Research$$c2024
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000287295 520__ $$aMetastasis formation is a complex process, involving multiple crucial steps, which are controlled by different regulatory mechanisms. In this context, the contribution of cancer metabolism to the metastatic cascade is being increasingly recognized. This Review focuses on changes in lipid metabolism that contribute to metastasis formation in solid tumors. We discuss the molecular mechanisms by which lipids induce a pro-metastatic phenotype and explore the role of lipids in response to oxidative stress and as signaling molecules. Finally, we reflect on potential avenues to target lipid metabolism to improve the treatment of metastatic cancers.
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000287295 7001_ $$00000-0002-2321-6504$$aChaves-Filho, Adriano B$$b1
000287295 7001_ $$0P:(DE-He78)94ae391f53fb9285e1b68f9930615af1$$aSchulze, Almut$$b2$$eLast author$$udkfz
000287295 773__ $$0PERI:(DE-600)3005299-3$$a10.1038/s43018-023-00702-z$$n1$$p16-29$$tNature cancer$$v5$$x2662-1347$$y2024
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