000287455 001__ 287455
000287455 005__ 20240229145759.0
000287455 0247_ $$2doi$$a10.1371/journal.pone.0270300
000287455 0247_ $$2pmid$$apmid:35749422
000287455 0247_ $$2pmc$$apmc:PMC9231817
000287455 037__ $$aDKFZ-2024-00247
000287455 041__ $$aEnglish
000287455 082__ $$a610
000287455 1001_ $$0P:(DE-He78)b7a0487a60da451c67d4b0fef6641ed8$$aAl-Shami, Kamal$$b0$$eFirst author$$udkfz
000287455 245__ $$aMotivators and barriers towards clinical research participation: A population-based survey from an Arab MENA country.
000287455 260__ $$aSan Francisco, California, US$$bPLOS$$c2022
000287455 3367_ $$2DRIVER$$aarticle
000287455 3367_ $$2DataCite$$aOutput Types/Journal article
000287455 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1706788085_16101
000287455 3367_ $$2BibTeX$$aARTICLE
000287455 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000287455 3367_ $$00$$2EndNote$$aJournal Article
000287455 500__ $$a#EA:A410#
000287455 520__ $$aJordan was the first Arab country to enact clinical research regulations. The country has a well-flourished pharmaceutical industry that leans heavily on clinical research (CR) for drug development and post-marketing surveillance. In this cross-sectional study, we sought to assess the public's awareness and attitude towards CR as well as their perceived motivators and barriers to CR participation. A population-based, self-administered questionnaire was distributed to the general public in Jordan. Among the 1061 participants in this survey, 74% reported being aware of CR. The majority (70%) agreed to the role of CR in health promotion. Online information and healthcare staff were the two main sources of CR information for the participants. About 25% of the participants received prior invitations to participate in CR with 21% agreeing to participate. However, most participants of the current study (63%) were willing to participate in future CR. Contributing to science, benefiting others, and promoting one's own health were the top motivating factors for participating in CR; while time constraints, fear of research procedure, and lack of interest were the most cited reasons for rejecting participation. Filling out questionnaire surveys, donating blood samples, and participating in physical examinations were the main CR contributions of the participants. Nearly 31% of the participants believed that CR is conducted in a responsible and ethical manner, while 57% did not have an opinion regarding the same matter. In addition, 49% and 44% were neutral with regards to the degree of harm and confidentiality posed by CR. While only 27% disagreed that CR exposes participants to some form of harm, 48% either strongly agreed (15%) or agreed (33%) that it maintains high level of confidentiality for participants. The current study provides insight into the public's perception of CR in Jordan as well as its motivating factors and perceived barriers towards participating in CR. We envisage to utilize this insight as an aid in the design of vigilant future awareness campaigns and recruitment strategies.
000287455 536__ $$0G:(DE-HGF)POF4-311$$a311 - Zellbiologie und Tumorbiologie (POF4-311)$$cPOF4-311$$fPOF IV$$x0
000287455 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de
000287455 650_2 $$2MeSH$$aArabs
000287455 650_2 $$2MeSH$$aAttitude
000287455 650_2 $$2MeSH$$aConfidentiality
000287455 650_2 $$2MeSH$$aCross-Sectional Studies
000287455 650_2 $$2MeSH$$aHumans
000287455 650_2 $$2MeSH$$aSurveys and Questionnaires
000287455 7001_ $$00000-0002-3441-2631$$aAhmed, Wesam S$$b1
000287455 7001_ $$00000-0002-2808-5099$$aAlzoubi, Karem H$$b2
000287455 773__ $$0PERI:(DE-600)2267670-3$$a10.1371/journal.pone.0270300$$gVol. 17, no. 6, p. e0270300 -$$n6$$pe0270300 -$$tPLOS ONE$$v17$$x1932-6203$$y2022
000287455 909CO $$ooai:inrepo02.dkfz.de:287455$$pVDB
000287455 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2022-04-12T10:14:32Z
000287455 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2022-04-12T10:14:32Z
000287455 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Anonymous peer review$$d2022-04-12T10:14:32Z
000287455 915__ $$0LIC:(DE-HGF)CCBYNV$$2V:(DE-HGF)$$aCreative Commons Attribution CC BY (No Version)$$bDOAJ$$d2022-04-12T10:14:32Z
000287455 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2023-10-25
000287455 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2023-10-25
000287455 9141_ $$y2022
000287455 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)b7a0487a60da451c67d4b0fef6641ed8$$aDeutsches Krebsforschungszentrum$$b0$$kDKFZ
000287455 9131_ $$0G:(DE-HGF)POF4-311$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vZellbiologie und Tumorbiologie$$x0
000287455 9200_ $$0I:(DE-He78)A410-20160331$$kA410$$lMetabolismus und Microenvironment$$x0
000287455 9201_ $$0I:(DE-He78)A410-20160331$$kA410$$lMetabolismus und Microenvironment$$x0
000287455 980__ $$ajournal
000287455 980__ $$aVDB
000287455 980__ $$aI:(DE-He78)A410-20160331
000287455 980__ $$aUNRESTRICTED