%0 Journal Article
%A Trkova, Katerina
%A Sumerauer, David
%A Bubenikova, Adela
%A Krskova, Lenka
%A Vicha, Ales
%A Koblizek, Miroslav
%A Zamecnik, Josef
%A Jurasek, Bruno
%A Kyncl, Martin
%A Malinova, Bela
%A Ondrova, Barbora
%A Jones, David T W
%A Sill, Martin
%A Strnadova, Martina
%A Stolova, Lucie
%A Misove, Adela
%A Benes, Vladimir
%A Zapotocky, Michal
%T Clinical and molecular study of radiation-induced gliomas.
%J Scientific reports
%V 14
%N 1
%@ 2045-2322
%C [London]
%I Macmillan Publishers Limited, part of Springer Nature
%M DKFZ-2024-00295
%P 3118
%D 2024
%X In this study, we provide a comprehensive clinical and molecular biological characterization of radiation-induced gliomas (RIG), including a risk assessment for developing gliomas. A cohort of 12 patients who developed RIG 9.5 years (3-31 years) after previous cranial radiotherapy for brain tumors or T-cell acute lymphoblastic leukemia was established. The derived risk of RIG development based on our consecutive cohort of 371 irradiated patients was 1.6
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38326438
%R 10.1038/s41598-024-53434-0
%U https://inrepo02.dkfz.de/record/287652