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@ARTICLE{Western:288060,
      author       = {B. Western and A. Ivarsson and I. Vistad and I. Demmelmaier
                      and N. K. Aaronson and G. Radcliffe and M. van Beurden and
                      M. Bohus and K. S. Courneya and A. J. Daley and D. A.
                      Galvão and R. Garrod and M. M. Goedendorp and K. A.
                      Griffith and W. H. van Harten and S. C. Hayes and F.
                      Herrero-Roman and A. E. Hiensch and M. L. Irwin and E. James
                      and M.-F. Kenkhuis and M. J. Kersten and H. Knoop and A.
                      Lucia and A. M. May and A. McConnachie and W. van Mechelen
                      and N. Mutrie and R. U. Newton and F. Nollet and H. S.
                      Oldenburg and R. Plotnikoff and M. E. Schmidt$^*$ and K. H.
                      Schmitz and K.-H. Schulz and C. E. Short and G. S. Sonke and
                      K. Steindorf$^*$ and M. M. Stuiver and D. R. Taaffe and L.
                      Thorsen and M. J. Velthuis and J. Wenzel and K. M.
                      Winters-Stone and J. Wiskemann$^*$ and S. Berntsen and L. M.
                      Buffart},
      title        = {{D}ropout from exercise trials among cancer survivors-{A}n
                      individual patient data meta-analysis from the {POLARIS}
                      study.},
      journal      = {Scandinavian journal of medicine $\&$ science in sports},
      volume       = {34},
      number       = {2},
      issn         = {0905-7188},
      address      = {Oxford [u.a.]},
      publisher    = {Wiley-Blackwell},
      reportid     = {DKFZ-2024-00318},
      pages        = {e14575},
      year         = {2024},
      abstract     = {The number of randomized controlled trials (RCTs)
                      investigating the effects of exercise among cancer survivors
                      has increased in recent years; however, participants
                      dropping out of the trials are rarely described. The
                      objective of the present study was to assess which
                      combinations of participant and exercise program
                      characteristics were associated with dropout from the
                      exercise arms of RCTs among cancer survivors.This study used
                      data collected in the Predicting OptimaL cAncer
                      RehabIlitation and Supportive care (POLARIS) study, an
                      international database of RCTs investigating the effects of
                      exercise among cancer survivors. Thirty-four exercise
                      trials, with a total of 2467 patients without metastatic
                      disease randomized to an exercise arm were included.
                      Harmonized studies included a pre and a posttest, and
                      participants were classified as dropouts when missing all
                      assessments at the post-intervention test. Subgroups were
                      identified with a conditional inference tree.Overall,
                      $9.6\%$ of the participants dropped out. Five subgroups were
                      identified in the conditional inference tree based on four
                      significant associations with dropout. Most dropout was
                      observed for participants with BMI >28.4 kg/m2 , performing
                      supervised resistance or unsupervised mixed exercise
                      $(19.8\%$ dropout) or had low-medium education and performed
                      aerobic or supervised mixed exercise $(13.5\%).$ The lowest
                      dropout was found for participants with BMI >28.4 kg/m2 and
                      high education performing aerobic or supervised mixed
                      exercise $(5.1\%),$ and participants with BMI ≤28.4 kg/m2
                      exercising during $(5.2\%)$ or post $(9.5\%)$
                      treatment.There are several systematic differences between
                      cancer survivors completing and dropping out from exercise
                      trials, possibly affecting the external validity of exercise
                      effects.},
      keywords     = {cancer (Other) / decision tree (Other) / exercise oncology
                      (Other) / individual patient data meta-analysis (Other)},
      cin          = {C110 / D120},
      ddc          = {796},
      cid          = {I:(DE-He78)C110-20160331 / I:(DE-He78)D120-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:38339809},
      doi          = {10.1111/sms.14575},
      url          = {https://inrepo02.dkfz.de/record/288060},
}