D440
Chronische Entzündung und Krebs
ID | I:(DE-He78)D440-20160331 |
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Coleman, O. I. ; Sorbie, A. ; Riva, A. ; von Stern, M. ; Kuhls, S. ; Selegato, D. M. ; Siegert, L. ; Keidel, I. ; Köhler, N. ; Wirbel, J. ; Kacprowski, T. ; Dunkel, A. ; Pauling, J. K. ; Plagge, J. ; Mediel-Cuadra, D. ; Wagner, S. J. ; Chadly, I. ; Bierwith, S. ; Peng, T. ; Metzler, T. ; Li, X.-F.DKFZ* ; Heikenwälder, M.DKFZ* ; Schafmayer, C. ; Hinz, S. ; Röder, C. ; Röcken, C. ; Zimmermann, M. ; Rosenstiel, P. ; Steiger, K. ; Jesinghaus, M. ; Liebisch, G. ; Ecker, J. ; Schmidt, C. ; Zeller, G. ; Janssen, K.-P. ; Haller, D.
ATF6 activation alters colonic lipid metabolism causing tumour-associated microbial adaptation.
Nature metabolism nn, nn (2025) [10.1038/s42255-025-01350-6]2025
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Harm, T. ; Rohlfing, A.-K. ; Henes, J. K. ; Manzat, N. ; Droppa, M. ; Bongers, M. ; Heikenwaelder, M.DKFZ* ; Müller, K. ; Gawaz, M. ; Rath, D.
Reduced Platelet Aggregation and Plasma Cytokine Levels Mitigate Progressive Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Journal of inflammation research 18, 11385 - 11400 (2025) [10.2147/JIR.S533707]2025
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Bremer, J. ; Nagel, J. ; Zschüntzsch, J. ; Zajt, K. K. ; Palaz, T. ; Blank, T. ; Ikis, A. ; Fischer, L. A. ; Sensmeyer, A. S. M. ; Wiechers, L. ; Reichelt, J. J. ; Hofmann, K.DKFZ* ; Wolf, M. J. ; Leuchtenberger, C.DKFZ* ; Tripathi, P. ; Einer, C. ; Zischka, H. ; Rothermel, U.DKFZ* ; Eck, A.-L.DKFZ* ; Reimann, R. ; Kana, V. ; Rushing, E. ; Aguzzi, A. ; Prinz, M. ; Liebetanz, D. ; Odoardi, F. ; Kuo, C.-C. ; Weis, J. ; Kraft, F. ; Schmidt, J. ; Heikenwälder, M. (Last author)DKFZ*
Mutual reinforcement of lymphotoxin-driven myositis and impaired autophagy in murine muscle.
Brain nn, nn (2025) [10.1093/brain/awaf260]2025
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Del Zompo, F. ; Crouchet, E. ; Ostyn, T. ; Nehme, Z. ; Messé, M. ; Juehling, F. ; Désert, R. ; Vieira, A. T. ; Moehlin, J. ; Nakib, D. ; Andrews, T. ; Perciani, C. ; Chung, S. ; Bader, G. ; McGilvray, I. ; Caime, C. ; Scaravaglio, M. ; Carbone, M. ; Invernizzi, P. ; Yaqub, S. ; Folseraas, T. ; Karlsen, T. H. ; Shankar, G. ; Primeaux, M. ; Dhawan, P. ; Banales, J. M. ; Roehlen, N. ; Iacone, R. ; Teixeira, G. ; Heikenwälder, M.DKFZ* ; Mailly, L. ; MacParland, S. ; Roskams, T. ; Govaere, O. ; Schuster, C. ; Baumert, T. F.
Claudin-1 is a mediator and therapeutic target in primary sclerosing cholangitis.
Journal of hepatology nn, nn (2025) [10.1016/j.jhep.2025.08.005]2025
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Vonficht, D. (First author)DKFZ* ; Jopp-Saile, L. (First author)DKFZ* ; Yousefian, S. ; Flore, V. ; Simó Vesperinas, I. ; Teuber, R. ; Avanesyan, B. ; Luo, Y. ; Röthemeier, C. ; Grünschläger, F.DKFZ* ; Fernandez-Vaquero, M.DKFZ* ; Fregona, V. ; Ordoñez-Rueda, D. ; Schmalbrock, L. K.DKFZ* ; Deininger, L. ; Yamachui Sitcheu, A. J. ; Gu, Z. ; Funk, M. C. ; Mikut, R. ; Heikenwälder, M.DKFZ* ; Eggert, A.DKFZ* ; von Stackelberg, A. ; Kobold, S.DKFZ* ; Krönke, J.DKFZ* ; Keller, U.DKFZ* ; Trumpp, A.DKFZ* ; Hegazy, A. N. ; Eckert, C. ; Hübschmann, D.DKFZ* ; Haas, S. (Last author)DKFZ*
Ultra-high-scale cytometry-based cellular interaction mapping.
Nature methods nn, nn (2025) [10.1038/s41592-025-02744-w]2025
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Siqin, S. (First author)DKFZ* ; Rahbari, M.DKFZ* ; Ernst, C.DKFZ* ; Grewe, I.DKFZ* ; Gunst, K.DKFZ* ; Neßling, M.DKFZ* ; Kaden, S.DKFZ* ; Richter, K.DKFZ* ; Häfele, L.DKFZ* ; Feuerbach, L.DKFZ* ; Krunic, D.DKFZ* ; Tessmer, C.DKFZ* ; Hofmann, I.DKFZ* ; Birgin, E. ; Brobeil, A. ; Rahbari, N. ; Heikenwälder, M.DKFZ* ; Bund, T. (Last author)DKFZ*
Expression of Bovine Meat and Milk Factor in Hepatocellular Carcinoma and Colorectal Liver Metastasis Patients.
Journal of medical virology 97(8), e70507 (2025) [10.1002/jmv.70507]2025
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Prawira, A. ; Xu, H. ; Mei, Y. ; Nasir, N. J. M. ; Reolo, M. J. Y. ; Otsuka, M. ; Leow, W. Q. ; Rahbari, M.DKFZ* ; Chen, Z.DKFZ* ; Weerasooriya, M. ; Abdullah, L. B. ; Wu, J. ; Hazirah, S. N. ; Wasser, M. ; Chung, A. ; Goh, B. K. ; Chow, P. K. ; Albani, S. ; Lee, J. ; Lim, T. K. H. ; Zhai, W. ; Dan, Y. Y. ; Goh, G. B. ; Heikenwälder, M.DKFZ* ; Zhang, Y. ; Dasgupta, R. ; Tai, W. M. D. ; Liu, H. ; Chen, J. ; Chew, V.
Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma.
Gut nn, nn (2025) [10.1136/gutjnl-2025-335084]2025
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Journal Article (Review Article)
Desert, R. ; Gianonne, F. ; Saviano, A. ; Hoshida, Y. ; Heikenwälder, M.DKFZ* ; Nahon, P. ; Baumert, T. F.
Improving immunotherapy for the treatment of hepatocellular carcinoma: learning from patients and preclinical models.
Gut and liver 2(1), 8 (2025) [10.1038/s44355-025-00018-y]2025
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Peighambari, A. ; Huang, H. ; Metzger, P. ; Adlesic, M. ; Zodel, K. ; Schäfer, S. ; Seidel, P. ; Braun, L. M. ; Hülsdünker, J. ; Melchinger, W. ; Follo, M. ; Ku, M. ; Haug, S. ; Li, Y. ; Köttgen, A. ; Schell, C. ; von Elverfeldt, D. ; Reichardt, W. ; Zeiser, R.DKFZ* ; Heikenwalder, M.DKFZ* ; Höfflin, R. ; Börries, M.DKFZ* ; Frew, I. J.DKFZ*
Characterisation of an autochthonous mouse ccRCC model of immune checkpoint inhibitor therapy resistance.
Scientific reports 15(1), 19818 (2025) [10.1038/s41598-025-04917-1]2025
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Siqin, S. (First author)DKFZ* ; Nikitina, E. (First author)DKFZ* ; Rahbari, M.DKFZ* ; Ernst, C.DKFZ* ; Krunic, D.DKFZ* ; Birgin, E. ; Tessmer, C.DKFZ* ; Hofmann, I.DKFZ* ; Rahbari, N. ; Bund, T. (First author)DKFZ*
Bovine Meat and Milk Factor (BMMF) Protein Is Expressed in Macrophages Spread Widely over the Mucosa of Colorectal Cancer Patients.
Cells 14(6), 455 (2025) [10.3390/cells14060455]2025
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