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@ARTICLE{Eisen:288151,
author = {C. K. Eisen and P. Liebig and J. Herrler and D. Ritter and
S. Lévy and M. Uder and A. Nagel$^*$ and D. Grodzki},
title = {{F}ast online spectral-spatial pulse design for
subject-specific fat saturation in cervical spine and foot
imaging at 1.5 {T}.},
journal = {Magnetic resonance materials in physics, biology and
medicine},
volume = {37},
number = {2},
issn = {0968-5243},
address = {Heidelberg},
publisher = {Springer},
reportid = {DKFZ-2024-00365},
pages = {257-272},
year = {2024},
note = {2024 Apr;37(2):257-272},
abstract = {To compensate subject-specific field inhomogeneities and
enhance fat pre-saturation with a fast online individual
spectral-spatial (SPSP) single-channel pulse design.The RF
shape is calculated online using subject-specific field maps
and a predefined excitation k-space trajectory. Calculation
acceleration options are explored to increase clinical
viability. Four optimization configurations are compared to
a standard Gaussian spectral selective pre-saturation pulse
and to a Dixon acquisition using phantom and volunteer (N =
5) data at 1.5 T with a turbo spin echo (TSE) sequence.
Measurements and simulations are conducted across various
body parts and image orientations.Phantom measurements
demonstrate up to a 3.5-fold reduction in residual fat
signal compared to Gaussian fat saturation. In vivo
evaluations show improvements up to sixfold for dorsal
subcutaneous fat in sagittal cervical spine acquisitions.
The versatility of the tailored trajectory is confirmed
through sagittal foot/ankle, coronal, and transversal
cervical spine experiments. Additional measurements indicate
that excitation field (B1) information can be disregarded at
1.5 T. Acceleration methods reduce computation time to a few
seconds.An individual pulse design that primarily
compensates for main field (B0) inhomogeneities in fat
pre-saturation is successfully implemented within an online
'push-button' workflow. Both fat saturation homogeneity and
the level of suppression are improved.},
keywords = {1.5 T MRI (Other) / Dynamic RF pulses (Other) / Dynamic
transmission (Other) / Fat saturation (Other) / Pulse design
(Other)},
cin = {E020},
ddc = {530},
cid = {I:(DE-He78)E020-20160331},
pnm = {315 - Bildgebung und Radioonkologie (POF4-315)},
pid = {G:(DE-HGF)POF4-315},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:38366129},
doi = {10.1007/s10334-024-01149-8},
url = {https://inrepo02.dkfz.de/record/288151},
}