%0 Journal Article
%A Harewood, Rhea
%A Rothwell, Joseph A
%A Bešević, Jelena
%A Viallon, Vivian
%A Achaintre, David
%A Gicquiau, Audrey
%A Rinaldi, Sabina
%A Wedekind, Roland
%A Prehn, Cornelia
%A Adamski, Jerzy
%A Schmidt, Julie A
%A Jacobs, Inarie
%A Tjønneland, Anne
%A Olsen, Anja
%A Severi, Gianluca
%A Kaaks, Rudolf
%A Katzke, Verena
%A Schulze, Matthias B
%A Prada, Marcela
%A Masala, Giovanna
%A Agnoli, Claudia
%A Panico, Salvatore
%A Sacerdote, Carlotta
%A Jakszyn, Paula Gabriela
%A Sánchez, Maria-Jose
%A Castilla, Jesús
%A Chirlaque, María-Dolores
%A Atxega, Amaia Aizpurua
%A van Guelpen, Bethany
%A Heath, Alicia K
%A Papier, Keren
%A Tong, Tammy Y N
%A Summers, Scott A
%A Playdon, Mary
%A Cross, Amanda J
%A Keski-Rahkonen, Pekka
%A Chajès, Véronique
%A Murphy, Neil
%A Gunter, Marc J
%T Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: a nested case-control study in the European Prospective Investigation into Cancer and Nutrition (EPIC).
%J EBioMedicine
%V 101
%@ 2352-3964
%C Amsterdam [u.a.]
%I Elsevier
%M DKFZ-2024-00438
%P 105024
%D 2024
%X Altered lipid metabolism is a hallmark of cancer development. However, the role of specific lipid metabolites in colorectal cancer development is uncertain.In a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC), we examined associations between pre-diagnostic circulating concentrations of 97 lipid metabolites (acylcarnitines, glycerophospholipids and sphingolipids) and colorectal cancer risk. Circulating lipids were measured using targeted mass spectrometry in 1591 incident colorectal cancer cases (55
%K Acylcarnitines (Other)
%K Colorectal cancer (Other)
%K Glycerophospholipids (Other)
%K Lipids (Other)
%K Metabolomics (Other)
%K Sphingolipids (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38412638
%R 10.1016/j.ebiom.2024.105024
%U https://inrepo02.dkfz.de/record/288729