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@ARTICLE{Aigner:288813,
      author       = {C. S. Aigner and S. Dietrich-Conzelmann and M. Lutz and F.
                      Krüger and S. Schmitter$^*$},
      title        = {{T}ailored and universal parallel transmit broadband pulses
                      for homogeneous 3{D} excitation of the human heart at 7{T}.},
      journal      = {Magnetic resonance in medicine},
      volume       = {92},
      number       = {2},
      issn         = {1522-2594},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2024-00484},
      pages        = {730-740},
      year         = {2024},
      note         = {#LA:E020# / 2024 Aug;92(2):730-740},
      abstract     = {To research and evaluate the performance of broadband
                      tailored kT-point pulses (TP) and universal pulses (UP) for
                      homogeneous excitation of the human heart at 7T.Relative 3D
                      B 1 + $$ {\mathrm{B}}_1^{+} $$ -maps of the thorax were
                      acquired from 29 healthy volunteers. TP and UP were designed
                      using the small-tip-angle approximation for a different
                      composition of up to seven resonance frequencies. TP were
                      computed for each of the 29 B 1 + $$ {\mathrm{B}}_1^{+} $$
                      -maps, and UPs were calculated using 22 B 1 + $$
                      {\mathrm{B}}_1^{+} $$ -maps and tested in seven testcases.
                      The performance of the pulses was analyzed using the
                      coefficient of variation (CV) in the 3D heart volumes. The
                      3D gradient-echo (GRE) scans were acquired for the seven
                      testcases to qualitatively validate the B 1 + $$
                      {\mathrm{B}}_1^{+} $$ -predictions.Single- and
                      double-frequency optimized pulses achieved homogeneity in
                      flip angle (FA) for the frequencies they were optimized for,
                      while the broadband pulses achieved uniformity in FA across
                      a 1300 Hz frequency range.Broadband TP and UP can be used
                      for homogeneous excitation of the heart volume across a 1300
                      Hz frequency range, including the water and the main six fat
                      peaks, or with longer pulse durations and higher FAs for a
                      smaller transmit bandwidth. Moreover, despite large
                      inter-volunteer variations, broadband UP can be used for
                      calibration-free 3D heart FA homogenization in time-critical
                      situations.},
      keywords     = {7 Tesla (Other) / body MRI (Other) / broadband (Other) /
                      parallel transmission (Other) / universal pulse (Other)},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:38440957},
      doi          = {10.1002/mrm.30072},
      url          = {https://inrepo02.dkfz.de/record/288813},
}