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024 7 _ |a 10.1002/mrm.30072
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024 7 _ |a 0740-3194
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037 _ _ |a DKFZ-2024-00484
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Aigner, Christoph Stefan
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245 _ _ |a Tailored and universal parallel transmit broadband pulses for homogeneous 3D excitation of the human heart at 7T.
260 _ _ |a New York, NY [u.a.]
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500 _ _ |a #LA:E020# / 2024 Aug;92(2):730-740
520 _ _ |a To research and evaluate the performance of broadband tailored kT-point pulses (TP) and universal pulses (UP) for homogeneous excitation of the human heart at 7T.Relative 3D B 1 + $$ {\mathrm{B}}_1^{+} $$ -maps of the thorax were acquired from 29 healthy volunteers. TP and UP were designed using the small-tip-angle approximation for a different composition of up to seven resonance frequencies. TP were computed for each of the 29 B 1 + $$ {\mathrm{B}}_1^{+} $$ -maps, and UPs were calculated using 22 B 1 + $$ {\mathrm{B}}_1^{+} $$ -maps and tested in seven testcases. The performance of the pulses was analyzed using the coefficient of variation (CV) in the 3D heart volumes. The 3D gradient-echo (GRE) scans were acquired for the seven testcases to qualitatively validate the B 1 + $$ {\mathrm{B}}_1^{+} $$ -predictions.Single- and double-frequency optimized pulses achieved homogeneity in flip angle (FA) for the frequencies they were optimized for, while the broadband pulses achieved uniformity in FA across a 1300 Hz frequency range.Broadband TP and UP can be used for homogeneous excitation of the heart volume across a 1300 Hz frequency range, including the water and the main six fat peaks, or with longer pulse durations and higher FAs for a smaller transmit bandwidth. Moreover, despite large inter-volunteer variations, broadband UP can be used for calibration-free 3D heart FA homogenization in time-critical situations.
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650 _ 7 |a 7 Tesla
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650 _ 7 |a body MRI
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650 _ 7 |a broadband
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650 _ 7 |a parallel transmission
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650 _ 7 |a universal pulse
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700 1 _ |a Dietrich-Conzelmann, Sebastian
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700 1 _ |a Lutz, Max
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700 1 _ |a Krüger, Felix
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700 1 _ |a Schmitter, Sebastian
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773 _ _ |a 10.1002/mrm.30072
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