%0 Journal Article
%A Gil-Lespinard, Mercedes
%A Almanza-Aguilera, Enrique
%A Castañeda, Jazmín
%A Guiñón-Fort, Daniel
%A Eriksen, Anne Kirstine
%A Tjønneland, Anne
%A Rothwell, Joseph A
%A Shah, Sanam
%A Cadeau, Claire
%A Katzke, Verena
%A Johnson, Theron
%A Schulze, Matthias B
%A Oliverio, Andreina
%A Pasanisi, Fabrizio
%A Tumino, Rosario
%A Manfredi, Luca
%A Masala, Giovana
%A Skeie, Guri
%A Lundblad, Marie Wasmuth
%A Brustad, Magritt
%A Lasheras, Cristina
%A Crous-Bou, Marta
%A Molina-Montes, Esther
%A Colorado-Yohar, Sandra
%A Guevara, Marcela
%A Amiano, Pilar
%A Johansson, Ingegerd
%A Hultdin, Johan
%A Forouhi, Nita G
%A Freisling, Heinz
%A Merdas, Mira
%A Debras, Charlotte
%A Heath, Alicia K
%A Aglago, Elom K
%A Aune, Dagfinn
%A Zamora-Ros, Raul
%T Plasma Concentration of 36 (Poly)phenols and Prospective Body Weight Change in Participants from the EPIC Cohort.
%J Annals of nutrition & metabolism
%V 80
%N 2
%@ 0250-6807
%C Basel
%I Karger
%M DKFZ-2024-00663
%P 87 - 100
%D 2024
%X Dietary intake of (poly)phenols has been linked to reduced adiposity and body weight (BW) in several epidemiological studies. However, epidemiological evidence on (poly)phenol biomarkers, particularly plasma concentrations, is scarce. We aimed to investigate the associations between plasma (poly)phenols and prospective BW change in participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.This study included 761 participants with data on BW at baseline and after 5 years of follow-up. Plasma concentrations of 36 (poly)phenols were measured at baseline using liquid chromatography-tandem mass spectrometry. Associations were assessed through general linear mixed models and multinomial logistic regression models, using change in BW as a continuous or as a categorical variable (BW loss, maintenance, gain), respectively. Plasma (poly)phenols were assessed as log2-transformed continuous variables. The false discovery rate (FDR) was used to control for multiple comparisons.Doubling plasma (poly)phenol concentrations showed a borderline trend towards a positive association with BW loss. Plasma vanillic acid showed the strongest association (-0.53 kg/5 years; 95
%K Humans
%K Phenols
%K Prospective Studies
%K Phenol
%K Body Weight
%K Neoplasms
%K Biomarkers
%K Body weight (Other)
%K Cohort (Other)
%K EPIC (Other)
%K Nutritional biomarker (Other)
%K Plasma (poly)phenol (Other)
%K Phenols (NLM Chemicals)
%K Phenol (NLM Chemicals)
%K Biomarkers (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38272006
%R 10.1159/000535803
%U https://inrepo02.dkfz.de/record/289229