TY  - JOUR
AU  - Gil-Lespinard, Mercedes
AU  - Almanza-Aguilera, Enrique
AU  - Castañeda, Jazmín
AU  - Guiñón-Fort, Daniel
AU  - Eriksen, Anne Kirstine
AU  - Tjønneland, Anne
AU  - Rothwell, Joseph A
AU  - Shah, Sanam
AU  - Cadeau, Claire
AU  - Katzke, Verena
AU  - Johnson, Theron
AU  - Schulze, Matthias B
AU  - Oliverio, Andreina
AU  - Pasanisi, Fabrizio
AU  - Tumino, Rosario
AU  - Manfredi, Luca
AU  - Masala, Giovana
AU  - Skeie, Guri
AU  - Lundblad, Marie Wasmuth
AU  - Brustad, Magritt
AU  - Lasheras, Cristina
AU  - Crous-Bou, Marta
AU  - Molina-Montes, Esther
AU  - Colorado-Yohar, Sandra
AU  - Guevara, Marcela
AU  - Amiano, Pilar
AU  - Johansson, Ingegerd
AU  - Hultdin, Johan
AU  - Forouhi, Nita G
AU  - Freisling, Heinz
AU  - Merdas, Mira
AU  - Debras, Charlotte
AU  - Heath, Alicia K
AU  - Aglago, Elom K
AU  - Aune, Dagfinn
AU  - Zamora-Ros, Raul
TI  - Plasma Concentration of 36 (Poly)phenols and Prospective Body Weight Change in Participants from the EPIC Cohort.
JO  - Annals of nutrition & metabolism
VL  - 80
IS  - 2
SN  - 0250-6807
CY  - Basel
PB  - Karger
M1  - DKFZ-2024-00663
SP  - 87 - 100
PY  - 2024
AB  - Dietary intake of (poly)phenols has been linked to reduced adiposity and body weight (BW) in several epidemiological studies. However, epidemiological evidence on (poly)phenol biomarkers, particularly plasma concentrations, is scarce. We aimed to investigate the associations between plasma (poly)phenols and prospective BW change in participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.This study included 761 participants with data on BW at baseline and after 5 years of follow-up. Plasma concentrations of 36 (poly)phenols were measured at baseline using liquid chromatography-tandem mass spectrometry. Associations were assessed through general linear mixed models and multinomial logistic regression models, using change in BW as a continuous or as a categorical variable (BW loss, maintenance, gain), respectively. Plasma (poly)phenols were assessed as log2-transformed continuous variables. The false discovery rate (FDR) was used to control for multiple comparisons.Doubling plasma (poly)phenol concentrations showed a borderline trend towards a positive association with BW loss. Plasma vanillic acid showed the strongest association (-0.53 kg/5 years; 95
KW  - Humans
KW  - Phenols
KW  - Prospective Studies
KW  - Phenol
KW  - Body Weight
KW  - Neoplasms
KW  - Biomarkers
KW  - Body weight (Other)
KW  - Cohort (Other)
KW  - EPIC (Other)
KW  - Nutritional biomarker (Other)
KW  - Plasma (poly)phenol (Other)
KW  - Phenols (NLM Chemicals)
KW  - Phenol (NLM Chemicals)
KW  - Biomarkers (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:38272006
DO  - DOI:10.1159/000535803
UR  - https://inrepo02.dkfz.de/record/289229
ER  -