%0 Journal Article
%A Singini, Mwiza Gideon
%A Muchengeti, Mazvita
%A Sitas, Freddy
%A Chen, Wenlong Carl
%A Combes, Jean-Damien
%A Waterboer, Tim
%A Clifford, Gary M
%T Antibodies against high-risk human papillomavirus proteins as markers for noncervical HPV-related cancers in a Black South African population, according to HIV status.
%J International journal of cancer
%V 155
%N 2
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2024-00681
%P 251-260
%D 2024
%Z 2024 Jul 15;155(2):251-260
%X Human papillomavirus (HPV) proteins may elicit antibody responses in the process toward HPV-related malignancy. However, HPV seroepidemiology in noncervical HPV-related cancers remains poorly understood, particularly in populations with a high prevalence of human immunodeficiency virus (HIV). Using a glutathione S-transferase-based multiplex serology assay, antibodies against E6, E7 and L1 proteins of HPV16 and HPV18 were measured in sera of 535 cases of noncervical HPV-related cancers (anal (n = 104), vulval (n = 211), vaginal (n = 49), penile (n = 37) and oropharyngeal (n = 134)) and 6651 non-infection-related cancer controls, from the Johannesburg Cancer Study that recruited Black South African with newly diagnosed cancer between 1995 and 2016. Logistic and Poisson regression models were used to calculate adjusted odds ratios (aOR) and prevalence ratios (aPR) and 95
%K Black South African (Other)
%K HIV status (Other)
%K human papillomavirus (Other)
%K noncervical HPV‐related cancers (Other)
%K proteins (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38577820
%R 10.1002/ijc.34919
%U https://inrepo02.dkfz.de/record/289286