%0 Journal Article
%A Hansford, Jordan R
%A Das, Anirban
%A McGee, Rose B
%A Nakano, Yoshiko
%A Brzezinski, Jack
%A Scollon, Sarah R
%A Rednam, Surya P
%A Schienda, Jaclyn
%A Michaeli, Orli
%A Kim, Sun Young
%A Greer, Mary-Louise C
%A Weksberg, Rosanna
%A Stewart, Douglas R
%A Foulkes, William D
%A Tabori, Uri
%A Pajtler, Kristian
%A Pfister, Stefan
%A Brodeur, Garrett M
%A Kamihara, Junne
%T Update on cancer predisposition syndromes and surveillance guidelines for childhood brain tumors.
%J Clinical cancer research
%V 30
%N 11
%@ 1078-0432
%C Philadelphia, Pa. [u.a.]
%I AACR
%M DKFZ-2024-00695
%P 2342-2350
%D 2024
%Z 2024 Jun 3;30(11):2342-2350
%X Tumors of the central nervous system (CNS) comprise the second most common group of neoplasms in childhood. The incidence of germline predisposition among children with brain tumors continues to grow as our knowledge on disease aetiology increases. Some children with brain tumors may present with non-malignant phenotypic features of specific syndromes (e.g. nevoid basal cell carcinoma syndrome, neurofibromatosis type 1 and type 2, DICER1 syndrome, and constitutional mismatch repair deficiency), while others may present with a strong family history of cancer (e.g. Li-Fraumeni syndrome), or with a rare tumor commonly found in the context of germline predisposition (e.g. rhabdoid tumor predisposition syndrome). Approximately 50
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38573059
%R 10.1158/1078-0432.CCR-23-4033
%U https://inrepo02.dkfz.de/record/289300