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@ARTICLE{Dietrich:289789,
author = {K. Dietrich$^*$ and S. Klüter and F. Dinkel$^*$ and G.
Echner$^*$ and S. Brons and S. Orzada$^*$ and J. Debus$^*$
and M. E. Ladd$^*$ and T. Platt$^*$},
title = {{A}n essentially radiation-transparent body coil integrated
with a patient rotation system for {MR}-guided particle
therapy.},
journal = {Medical physics},
volume = {51},
number = {6},
issn = {0094-2405},
address = {College Park, Md.},
publisher = {AAPM},
reportid = {DKFZ-2024-00868},
pages = {4028-4043},
year = {2024},
note = {#EA:E020#EA:E050#LA:E020#LA:E050# / 2024
Jun;51(6):4028-4043},
abstract = {The pursuit of adaptive radiotherapy using MR imaging for
better precision in patient positioning puts stringent
demands on the hardware components of the MR scanner.
Particularly in particle therapy, the dose distribution and
thus the efficacy of the treatment is susceptible to beam
attenuation from interfering materials in the irradiation
path. This severely limits the usefulness of conventional
imaging coils, which contain highly attenuating parts such
as capacitors and preamplifiers in an unknown position, and
requires development of a dedicated radiofrequency (RF) coil
with close consideration of the materials and components
used.In MR-guided radiation therapy in the human torso,
imaging coils with a large FOV and homogeneous B1 field
distribution are required for reliable tissue
classification. In this work, an imaging coil for MR-guided
particle therapy was developed with minimal ion attenuation
while maintaining flexibility in treatment.A birdcage coil
consisting of nearly radiation-transparent materials was
designed and constructed for a closed-bore 1.5 T MR system.
Additionally, the coil was mounted on a rotatable patient
capsule for flexible positioning of the patient relative to
the beam. The ion attenuation of the RF coil was
investigated in theory and via measurements of the Bragg
peak position. To characterize the imaging quality of the RF
coil, transmit and receive field distributions were
simulated and measured inside a homogeneous
tissue-simulating phantom for various rotation angles of the
patient capsule ranging from 0° to 345° in steps of 15°.
Furthermore, simulations with a heterogeneous human voxel
model were performed to better estimate the effect of real
patient loading, and the RF coil was compared to the
internal body coil in terms of SNR for a full rotation of
the patient capsule.The RF coil (total water equivalent
thickness (WET) ≈ 420 µm, WET of conductor ≈ 210 µm)
can be considered to be radiation-transparent, and a
measured transmit power efficiency (B1 +/ P $\sqrt
{\mathrm{P}} $ ) between 0.17 µT/ W $\sqrt {\mathrm{W}} $
and 0.26 µT/ W $\sqrt {\mathrm{W}} $ could be achieved in a
volume (Δz = 216 mm, complete x and y range) for the 24
investigated rotation angles of the patient capsule.
Furthermore, homogeneous transmit and receive field
distributions were measured and simulated in the transverse,
coronal and sagittal planes in a homogeneous phantom and a
human voxel model. In addition, the SNR of the
radiation-transparent RF coil varied between 103 and 150, in
the volume (Δz = 216 mm) of a homogeneous phantom and
surpasses the SNR of the internal body coil for all rotation
angles of the patient capsule.A radiation-transparent RF
coil was developed and built that enables flexible patient
to beam positioning via full rotation capability of the RF
coil and patient relative to the beam, with results
providing promising potential for adaptive MR-guided
particle therapy.},
keywords = {MR‐guided particle therapy (Other) / interventional MRI
(Other) / rotatable body coil (Other)},
cin = {E020 / E050 / HD01 / E040},
ddc = {610},
cid = {I:(DE-He78)E020-20160331 / I:(DE-He78)E050-20160331 /
I:(DE-He78)HD01-20160331 / I:(DE-He78)E040-20160331},
pnm = {315 - Bildgebung und Radioonkologie (POF4-315)},
pid = {G:(DE-HGF)POF4-315},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:38656549},
doi = {10.1002/mp.17065},
url = {https://inrepo02.dkfz.de/record/289789},
}