% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Liang:289950,
      author       = {Q. Liang$^*$ and T. Mukama$^*$ and K. Sundquist and J.
                      Sundquist and H. Brenner$^*$ and E. Kharazmi$^*$ and M.
                      Fallah$^*$},
      title        = {{L}onger {I}nterval {B}etween {F}irst {C}olonoscopy {W}ith
                      {N}egative {F}indings for {C}olorectal {C}ancer and {R}epeat
                      {C}olonoscopy.},
      journal      = {JAMA oncology},
      volume       = {10},
      number       = {7},
      issn         = {2374-2437},
      address      = {Chicago, Ill.},
      publisher    = {American Medical Association},
      reportid     = {DKFZ-2024-00932},
      pages        = {866-873},
      year         = {2024},
      note         = {#EA:C120#LA:C120# / 2024 Jul 1;10(7):866-873},
      abstract     = {For individuals without a family history of colorectal
                      cancer (CRC), colonoscopy screening every 10 years is
                      recommended to reduce CRC incidence and mortality. However,
                      debate exists about whether and for how long this 10-year
                      interval could be safely expanded.To assess how many years
                      after a first colonoscopy with findings negative for CRC a
                      second colonoscopy can be performed.This cohort study
                      leveraged Swedish nationwide register-based data to examine
                      CRC diagnoses and CRC-specific mortality among individuals
                      without a family history of CRC. The exposed group included
                      individuals who had a first colonoscopy with findings
                      negative for CRC at age 45 to 69 years between 1990 and
                      2016. The control group included individuals matched by sex,
                      birth year, and baseline age (ie, the age of their matched
                      exposed individual when the exposed individual's first
                      colonoscopy with findings negative for CRC was performed).
                      Individuals in the control group either did not have a
                      colonoscopy during the follow-up or underwent colonoscopy
                      that resulted in a CRC diagnosis. Up to 18 controls were
                      matched with each exposed individual. Individuals were
                      followed up from 1990 to 2018, and data were analyzed from
                      November 2022 to November 2023.A first colonoscopy with
                      findings negative for CRC, defined as a first colonoscopy
                      without a diagnosis of colorectal polyp, adenoma, carcinoma
                      in situ, or CRC before or within 6 months after
                      screening.The primary outcomes were CRC diagnosis and
                      CRC-specific death. The 10-year standardized incidence ratio
                      and standardized mortality ratio were calculated to compare
                      risks of CRC and CRC-specific death in the exposed and
                      control groups based on different follow-up screening
                      intervals.The sample included 110 074 individuals (65 147
                      females $[59.2\%])$ in the exposed group and 1 981 332 (1
                      172 646 females $[59.2\%])$ in the control group. The median
                      (IQR) age for individuals in both groups was 59 (52-64)
                      years. During up to 29 years of follow-up of individuals
                      with a first colonoscopy with findings negative for CRC, 484
                      incident CRCs and 112 CRC-specific deaths occurred. After a
                      first colonoscopy with findings negative for CRC, the risks
                      of CRC and CRC-specific death in the exposed group were
                      significantly lower than those in their matched controls for
                      15 years. At 15 years after a first colonoscopy with
                      findings negative for CRC, the 10-year standardized
                      incidence ratio was 0.72 $(95\%$ CI, 0.54-0.94) and the
                      10-year standardized mortality ratio was 0.55 $(95\%$ CI,
                      0.29-0.94). In other words, the 10-year cumulative risk of
                      CRC in year 15 in the exposed group was $72\%$ that of the
                      10-year cumulative risk of CRC in the control group.
                      Extending the colonoscopy screening interval from 10 to 15
                      years in individuals with a first colonoscopy with findings
                      negative for CRC could miss the early detection of only 2
                      CRC cases and the prevention of 1 CRC-specific death per
                      1000 individuals, while potentially avoiding 1000
                      colonoscopies.This cohort study found that for the
                      population without a family history of CRC, the 10-year
                      interval between colonoscopy screenings for individuals with
                      a first colonoscopy with findings negative for CRC could
                      potentially be extended to 15 years. A longer interval
                      between colonoscopy screenings could be beneficial in
                      avoiding unnecessary invasive examinations.},
      cin          = {C120 / C070 / HD01},
      ddc          = {610},
      cid          = {I:(DE-He78)C120-20160331 / I:(DE-He78)C070-20160331 /
                      I:(DE-He78)HD01-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:38696176},
      doi          = {10.1001/jamaoncol.2024.0827},
      url          = {https://inrepo02.dkfz.de/record/289950},
}