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@ARTICLE{StevensonHoare:291664,
      author       = {J. Stevenson-Hoare$^*$ and H. Stocker and K. Trares$^*$ and
                      B. Holleczek and H. Brenner$^*$},
      title        = {{S}ubjective hearing and memory problems are associated
                      with dementia and cognition in later life.},
      journal      = {Alzheimer's $\&$ dementia / Diagnosis, assessment $\&$
                      disease monitoring},
      volume       = {16},
      number       = {3},
      issn         = {2352-8729},
      address      = {Hoboken, NJ},
      publisher    = {Wiley},
      reportid     = {DKFZ-2024-01485},
      pages        = {e12624},
      year         = {2024},
      note         = {#EA:C070#LA:C070#},
      abstract     = {Subjective hearing and memory problems are detectable
                      earlier than objective measures of sensory loss and
                      cognitive decline, which are known to be related to an
                      increased risk of dementia in later life.Using a
                      population-representative cohort of 6006 individuals (aged
                      50-75) we examined whether participants who self-reported
                      hearing and short-term memory issues showed greater rates of
                      dementia within 17 years of follow-up. A sub-cohort was
                      tested for audiometric threshold and cognition after 14
                      years.Hearing and memory problems were associated with a
                      greater risk of dementia (hazard ratios [HRs] = 1.42 $[95\%$
                      confidence interval: 1.11-1.81], 1.57 [1.30-1.90]), and
                      poorer cognition 14 years later. The risk was greatest in
                      those reporting both problems (HR = 1.99 [1.42-2.80]). At
                      follow-up, the level of hearing loss was associated with
                      lower cognitive scores.Self-reports of hearing and
                      short-term memory problems are associated with poorer
                      cognitive performance and a greater risk of dementia.
                      Subjective assessments may have predictive power over more
                      than a decade.In a sample of older adults subjective hearing
                      and memory problems were associated with dementia
                      risk.Cross-sectionally, the audiometric screening threshold
                      was associated with cognitive test scores.Subjective sensory
                      and memory loss questions are easy to implement and show
                      good predictive power.},
      keywords     = {cognitive decline (Other) / cohort study (Other) / dementia
                      (Other) / hearing (Other) / memory (Other)},
      cin          = {C070},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39011236},
      pmc          = {pmc:PMC11247363},
      doi          = {10.1002/dad2.12624},
      url          = {https://inrepo02.dkfz.de/record/291664},
}