TY  - JOUR
AU  - Grözinger, Martin
AU  - Wennmann, Markus
AU  - Sawall, Stefan
AU  - Wehrse, Eckhard
AU  - Sedaghat, Sam
AU  - Neelsen, Christian
AU  - Bauer, Fabian
AU  - Goldschmidt, Hartmut
AU  - Weru, Vivienn
AU  - Ziener, Christian H
AU  - Kopp-Schneider, Annette
AU  - Schlemmer, Heinz-Peter
AU  - Rotkopf, Lukas Thomas
TI  - Detection of myeloma-associated osteolytic bone lesions with energy-integrating and photon-counting detector CT .[Erkennung myelomassoziierter osteolytischer Knochenläsionen mit energieintegrierender und photonenzählender Detektor-Computertomographie].
JO  - Die Radiologie
VL  - 64
IS  - Suppl 1
SN  - 2731-7048
CY  - [Berlin]
PB  - Springer Medizin Verlag GmbH
M1  - DKFZ-2024-01491
SP  - 24-31
PY  - 2024
N1  - #EA:E010#LA:E010# / 2024 Nov;64(Suppl 1):24-31
AB  - A recent innovation in computed tomography (CT) imaging has been the introduction of photon-counting detector CT (PCD-CT) systems, which are able to register the number and the energy level of incoming x‑ray photons and have smaller detector elements compared with conventional CT scanners that operate with energy-integrating detectors (EID-CT).The study aimed to evaluate the potential benefits of a novel, non-CE certified PCD-CT in detecting myeloma-associated osteolytic bone lesions (OL) compared with a state-of-the-art EID-CT.Nine patients with multiple myeloma stage III (according to Durie and Salmon) underwent magnetic resonance imaging (MRI), EID-CT, and PCD-CT of the lower lumbar spine and pelvis. The PCD-CT and EID-CT images of all myeloma lesions that were visible in clinical MRI scans were reviewed by three radiologists for corresponding OL. Additionally, the visualization of destructions to cancellous or cortical bone, and trabecular structures, was compared between PCD-CT and EID-CT.Readers detected 21
KW  - Image quality (Other)
KW  - Lesion detection (Other)
KW  - Multiple myeloma (Other)
KW  - Osteolytic lesions (Other)
KW  - Photon-counting CT (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39020050
DO  - DOI:10.1007/s00117-024-01344-7
UR  - https://inrepo02.dkfz.de/record/291687
ER  -