TY  - JOUR
AU  - Huybrechts, Inge
AU  - Chimera, Bernadette
AU  - Hanley-Cook, Giles T
AU  - Biessy, Carine
AU  - Deschasaux-Tanguy, Mélanie
AU  - Touvier, Mathilde
AU  - Kesse-Guyot, Emmanuelle
AU  - Srour, Bernard
AU  - Baudry, Julia
AU  - Berlivet, Justine
AU  - Casagrande, Corinne
AU  - Nicolas, Geneviève
AU  - Lopez, Jessica Blanco
AU  - Millett, Christopher J
AU  - Cakmak, Emine Koc
AU  - Robinson, Oliver J K
AU  - Murray, Kris A
AU  - Schulze, Matthias B
AU  - Masala, Giovanna
AU  - Guevara, Marcela
AU  - Bodén, Stina
AU  - Cross, Amanda J
AU  - Tsilidis, Kostas
AU  - Heath, Alicia K
AU  - Panico, Salvatore
AU  - Amiano, Pilar
AU  - Huerta, José Ma
AU  - Key, Tim
AU  - Ericson, Ulrika
AU  - Stocks, Tanja
AU  - Lundblad, Marie Wasmuth
AU  - Skeie, Guri
AU  - Sacerdote, Carlotta
AU  - Katzke, Verena
AU  - Playdon, Mary C
AU  - Ferrari, Pietro
AU  - Vineis, Paolo
AU  - Lachat, Carl
AU  - Gunter, Marc J
TI  - Food biodiversity and gastrointestinal cancer risk in nine European countries: Analysis within a prospective cohort study.
JO  - European journal of cancer
VL  - 210
SN  - 0014-2964
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DKFZ-2024-01704
SP  - 114258
PY  - 2024
AB  - Food biodiversity in human diets has potential co-benefits for both public health and sustainable food systems. However, current evidence on the potential relationship between food biodiversity and cancer risk, and particularly gastrointestinal cancers typically related to diet, remains limited. This study evaluated how dietary species richness (DSR) was associated with gastrointestinal cancer risk in a pan-European population.Associations between DSR and subsequent gastrointestinal cancer risk were examined among 450,111 adults enrolled in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC, initiated in 1992), free of cancer at baseline. Usual dietary intakes were assessed at recruitment with country-specific dietary questionnaires. DSR of an individual's yearly diet was calculated based on the absolute number of unique biological species in each food and drink item. Associations between DSR and cancer risk were assessed by multivariable Cox proportional hazards regression models.During a median follow-up time of 14.1 years (SD=3.9), 10,705 participants were diagnosed with gastrointestinal cancer. Hazard ratios (HRs) and 95 
LB  - PUB:(DE-HGF)16
C6  - pmid:39168001
DO  - DOI:10.1016/j.ejca.2024.114258
UR  - https://inrepo02.dkfz.de/record/292355
ER  -