%0 Journal Article
%A Zuern, Kosima
%A Hielscher, Thomas
%A Werly, Annika
%A Breitkreutz, Iris
%A Sauer, Sandra
%A Raab, Marc S
%A Müller-Tidow, Carsten
%A Goldschmidt, Hartmut
%A Mai, Elias K
%T Longitudinal assessment of established risk stratification models in patients with monoclonal gammopathy of undetermined significance.
%J Blood cancer journal
%V 14
%N 1
%@ 2044-5385
%C London [u.a.]
%I Nature Publishing Group
%M DKFZ-2024-01740
%P 148
%D 2024
%X Risk of progression of monoclonal gammopathy of undetermined significance (MGUS) into multiple myeloma and related plasma cell disorders can be determined by three major risk stratification models, namely Mayo2005, Sweden2014, and NCI2019. This retrospective study of 427 patients with MGUS diagnosed according to the 2014 International Myeloma Working Group criteria aimed to describe and analyze the longitudinal applicability of these risk models. In all three models, the majority of patients remained at their baseline risk group, whereas small numbers of patients migrated to a different risk group. Proportions of patients among risk groups remained stable over time (e.g. Mayo2005 model, low-risk group, at baseline: 43
%K Humans
%K Monoclonal Gammopathy of Undetermined Significance: epidemiology
%K Monoclonal Gammopathy of Undetermined Significance: diagnosis
%K Male
%K Female
%K Aged
%K Middle Aged
%K Disease Progression
%K Retrospective Studies
%K Risk Assessment
%K Aged, 80 and over
%K Longitudinal Studies
%K Adult
%K Multiple Myeloma: epidemiology
%K Multiple Myeloma: diagnosis
%K Risk Factors
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39191769
%2 pmc:PMC11349746
%R 10.1038/s41408-024-01126-3
%U https://inrepo02.dkfz.de/record/292493