TY  - JOUR
AU  - Zuern, Kosima
AU  - Hielscher, Thomas
AU  - Werly, Annika
AU  - Breitkreutz, Iris
AU  - Sauer, Sandra
AU  - Raab, Marc S
AU  - Müller-Tidow, Carsten
AU  - Goldschmidt, Hartmut
AU  - Mai, Elias K
TI  - Longitudinal assessment of established risk stratification models in patients with monoclonal gammopathy of undetermined significance.
JO  - Blood cancer journal
VL  - 14
IS  - 1
SN  - 2044-5385
CY  - London [u.a.]
PB  - Nature Publishing Group
M1  - DKFZ-2024-01740
SP  - 148
PY  - 2024
AB  - Risk of progression of monoclonal gammopathy of undetermined significance (MGUS) into multiple myeloma and related plasma cell disorders can be determined by three major risk stratification models, namely Mayo2005, Sweden2014, and NCI2019. This retrospective study of 427 patients with MGUS diagnosed according to the 2014 International Myeloma Working Group criteria aimed to describe and analyze the longitudinal applicability of these risk models. In all three models, the majority of patients remained at their baseline risk group, whereas small numbers of patients migrated to a different risk group. Proportions of patients among risk groups remained stable over time (e.g. Mayo2005 model, low-risk group, at baseline: 43
KW  - Humans
KW  - Monoclonal Gammopathy of Undetermined Significance: epidemiology
KW  - Monoclonal Gammopathy of Undetermined Significance: diagnosis
KW  - Male
KW  - Female
KW  - Aged
KW  - Middle Aged
KW  - Disease Progression
KW  - Retrospective Studies
KW  - Risk Assessment
KW  - Aged, 80 and over
KW  - Longitudinal Studies
KW  - Adult
KW  - Multiple Myeloma: epidemiology
KW  - Multiple Myeloma: diagnosis
KW  - Risk Factors
LB  - PUB:(DE-HGF)16
C6  - pmid:39191769
C2  - pmc:PMC11349746
DO  - DOI:10.1038/s41408-024-01126-3
UR  - https://inrepo02.dkfz.de/record/292493
ER  -