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000292555 1001_ $$00009-0005-8821-1471$$aManuilova, Iryna$$b0
000292555 245__ $$aIdentifications of Similarity Metrics for Patients With Cancer: Protocol for a Scoping Review.
000292555 260__ $$aToronto$$b[Verlag nicht ermittelbar]$$c2024
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000292555 520__ $$aUnderstanding the similarities of patients with cancer is essential to advancing personalized medicine, improving patient outcomes, and developing more effective and individualized treatments. It enables researchers to discover important patterns, biomarkers, and treatment strategies that can have a significant impact on cancer research and oncology. In addition, the identification of previously successfully treated patients supports oncologists in making treatment decisions for a new patient who is clinically or molecularly similar to the previous patient.The planned review aims to systematically summarize, map, and describe existing evidence to understand how patient similarity is defined and used in cancer research and clinical care.To systematically identify relevant studies and to ensure reproducibility and transparency of the review process, a comprehensive literature search will be conducted in several bibliographic databases, including Web of Science, PubMed, LIVIVIVO, and MEDLINE, covering the period from 1998 to February 2024. After the initial duplicate deletion phase, a study selection phase will be applied using Rayyan, which consists of 3 distinct steps: title and abstract screening, disagreement resolution, and full-text screening. To ensure the integrity and quality of the selection process, each of these steps is preceded by a pilot testing phase. This methodological process will culminate in the presentation of the final research results in a structured form according to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) flowchart. The protocol has been registered in the Journal of Medical Internet Research.This protocol outlines the methodologies used in conducting the scoping review. A search of the specified electronic databases and after removing duplicates resulted in 1183 unique records. As of March 2024, the review process has moved to the full-text evaluation phase. At this stage, data extraction will be conducted using a pretested chart template.The scoping review protocol, centered on these main concepts, aims to systematically map the available evidence on patient similarity among patients with cancer. By defining the types of data sources, approaches, and methods used in the field, and aligning these with the research questions, the review will provide a foundation for future research and clinical application in personalized cancer care. This protocol will guide the literature search, data extraction, and synthesis of findings to achieve the review's objectives.DERR1-10.2196/58705.
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000292555 650_7 $$2Other$$acancer research
000292555 650_7 $$2Other$$acancer similarity metrics
000292555 650_7 $$2Other$$apatient similarity
000292555 650_7 $$2Other$$apatient similarity applications
000292555 650_7 $$2Other$$aprecision medicine
000292555 650_7 $$2Other$$ascoping review protocol
000292555 650_2 $$2MeSH$$aHumans
000292555 650_2 $$2MeSH$$aNeoplasms: therapy
000292555 650_2 $$2MeSH$$aResearch Design
000292555 650_2 $$2MeSH$$aPrecision Medicine: methods
000292555 650_2 $$2MeSH$$aReproducibility of Results
000292555 7001_ $$00009-0001-7946-8559$$aBossenz, Jan$$b1
000292555 7001_ $$00009-0003-6925-5941$$aWeise, Annemarie Bianka$$b2
000292555 7001_ $$00009-0001-2887-7109$$aBoehm, Dominik$$b3
000292555 7001_ $$00009-0007-3980-8233$$aStrantz, Cosima$$b4
000292555 7001_ $$00000-0002-1269-9360$$aUnberath, Philipp$$b5
000292555 7001_ $$00000-0002-0491-3929$$aReimer, Niklas$$b6
000292555 7001_ $$0P:(DE-He78)374d2ab968929c8e96e9c227b676d7ab$$aMetzger, Patrick$$b7$$udkfz
000292555 7001_ $$00000-0002-8381-6624$$aPauli, Thomas$$b8
000292555 7001_ $$00000-0002-5153-0269$$aWerle, Silke D$$b9
000292555 7001_ $$00000-0002-3856-7956$$aSchulze, Susann$$b10
000292555 7001_ $$00009-0004-2886-9485$$aHiemer, Sonja$$b11
000292555 7001_ $$00000-0002-1014-4521$$aUstjanzew, Arsenij$$b12
000292555 7001_ $$00000-0002-4759-5254$$aKestler, Hans A$$b13
000292555 7001_ $$aBusch, Hauke$$b14
000292555 7001_ $$0P:(DE-He78)fc949170377b58098e46141d95c72661$$aBrors, Benedikt$$b15$$udkfz
000292555 7001_ $$00000-0003-4369-3591$$aChristoph, Jan$$b16
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