TY  - JOUR
AU  - Safizadeh, Fatemeh
AU  - Mandic, Marko
AU  - Hoffmeister, Michael
AU  - Brenner, Hermann
TI  - Reevaluating the fraction of cancer attributable to excess weight: overcoming the hidden impact of prediagnostic weight loss.
JO  - European journal of epidemiology
VL  - 39
IS  - 9
SN  - 0393-2990
CY  - Dordrecht [u.a.]
PB  - Springer Science + Business Media B.V.
M1  - DKFZ-2024-01883
SP  - 991-1003
PY  - 2024
N1  - #EA:C070#LA:C070#LA:C120# / 2024 Sep;39(9):991-1003
AB  - To evaluate the magnitude of the potential underestimation of the proportion of cancer cases attributable to excess weight, known as population attributable fraction (PAF), due to potential bias from prediagnostic weight loss already present at baseline of cohort studies and to overcome it as much as possible.Data from the UK Biobank cohort participants aged 40-69 without prior cancer diagnosis were analyzed. We assessed the magnitude of associations of excess weight with the incidence of obesity-related cancers combined, and separately for gastrointestinal (GI) and other cancers. Using multivariable Cox proportional hazards models, hazard ratios (HR) and their 95
KW  - Body mass index (Other)
KW  - Cancer (Other)
KW  - Obesity (Other)
KW  - Overweight (Other)
KW  - Population attributable fraction (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39294524
DO  - DOI:10.1007/s10654-024-01146-0
UR  - https://inrepo02.dkfz.de/record/293335
ER  -