%0 Journal Article
%A Liang, Linda A
%A Tanaka, Luana F
%A Radde, Kathrin
%A Bussas, Ulrike
%A Ikenberg, Hans
%A Heideman, Daniëlle A M
%A Meijer, Chris J L M
%A Blettner, Maria
%A Klug, Stefanie J
%T Population-based age- and type-specific prevalence of human papillomavirus among non-vaccinated women aged 30 years and above in Germany.
%J BMC infectious diseases
%V 24
%N 1
%@ 1471-2334
%C Heidelberg
%I Springer
%M DKFZ-2024-01894
%P 1008
%D 2024
%X A persisting high-risk human papillomavirus (HR-HPV) infection is causal for cervical cancer; however, there is limited population-based data on the prevalence of HPV infections in Germany. We assessed the age and type-specific HPV prevalence, and associated risk factors in HPV unvaccinated women aged 30 and above.The MARZY prospective population-based cohort study was conducted between 2005 and 2012 in Mainz and Mainz-Bingen, Germany. Eligible women were randomly recruited from population registries and invited for cervical cancer screening (n = 5,275). A study swab (liquid-based cytology) was taken and HPV testing was performed with GP5+/6 + polymerase chain reaction (PCR) followed by genotyping. We assessed HPV types as HR-HPV, 'moderate' risk and low-risk (LR-HPV). Logistic regression was performed to identify factors associated with HPV infection, stratified by HPV types.2,520 women were screened with a valid PCR result. Overall HPV prevalence was 10.6
%K Humans
%K Female
%K Papillomavirus Infections: epidemiology
%K Papillomavirus Infections: virology
%K Germany: epidemiology
%K Adult
%K Prevalence
%K Middle Aged
%K Papillomaviridae: genetics
%K Papillomaviridae: classification
%K Papillomaviridae: isolation & purification
%K Prospective Studies
%K Risk Factors
%K Aged
%K Age Factors
%K Uterine Cervical Neoplasms: epidemiology
%K Uterine Cervical Neoplasms: virology
%K Genotype
%K Human Papillomavirus Viruses
%K Cervical cancer screening (Other)
%K Germany (Other)
%K Human papillomavirus (Other)
%K Prevalence (Other)
%K Risk factors (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39300354
%R 10.1186/s12879-024-09827-7
%U https://inrepo02.dkfz.de/record/293348