TY  - JOUR
AU  - Liang, Linda A
AU  - Tanaka, Luana F
AU  - Radde, Kathrin
AU  - Bussas, Ulrike
AU  - Ikenberg, Hans
AU  - Heideman, Daniëlle A M
AU  - Meijer, Chris J L M
AU  - Blettner, Maria
AU  - Klug, Stefanie J
TI  - Population-based age- and type-specific prevalence of human papillomavirus among non-vaccinated women aged 30 years and above in Germany.
JO  - BMC infectious diseases
VL  - 24
IS  - 1
SN  - 1471-2334
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2024-01894
SP  - 1008
PY  - 2024
AB  - A persisting high-risk human papillomavirus (HR-HPV) infection is causal for cervical cancer; however, there is limited population-based data on the prevalence of HPV infections in Germany. We assessed the age and type-specific HPV prevalence, and associated risk factors in HPV unvaccinated women aged 30 and above.The MARZY prospective population-based cohort study was conducted between 2005 and 2012 in Mainz and Mainz-Bingen, Germany. Eligible women were randomly recruited from population registries and invited for cervical cancer screening (n = 5,275). A study swab (liquid-based cytology) was taken and HPV testing was performed with GP5+/6 + polymerase chain reaction (PCR) followed by genotyping. We assessed HPV types as HR-HPV, 'moderate' risk and low-risk (LR-HPV). Logistic regression was performed to identify factors associated with HPV infection, stratified by HPV types.2,520 women were screened with a valid PCR result. Overall HPV prevalence was 10.6
KW  - Humans
KW  - Female
KW  - Papillomavirus Infections: epidemiology
KW  - Papillomavirus Infections: virology
KW  - Germany: epidemiology
KW  - Adult
KW  - Prevalence
KW  - Middle Aged
KW  - Papillomaviridae: genetics
KW  - Papillomaviridae: classification
KW  - Papillomaviridae: isolation & purification
KW  - Prospective Studies
KW  - Risk Factors
KW  - Aged
KW  - Age Factors
KW  - Uterine Cervical Neoplasms: epidemiology
KW  - Uterine Cervical Neoplasms: virology
KW  - Genotype
KW  - Human Papillomavirus Viruses
KW  - Cervical cancer screening (Other)
KW  - Germany (Other)
KW  - Human papillomavirus (Other)
KW  - Prevalence (Other)
KW  - Risk factors (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39300354
DO  - DOI:10.1186/s12879-024-09827-7
UR  - https://inrepo02.dkfz.de/record/293348
ER  -