%0 Journal Article
%A Ostau, Nicola Edith von
%A Handke, Analena Elisa
%A Wiesenfarth, Manuel
%A Albers, Peter
%A Antoch, Gerald
%A Noldus, Joachim
%A Reis, Henning
%A Cotarelo, Cristina
%A Preetz, Julia
%A Umutlu, Lale
%A Ingenwerth, Marc
%A Radtke, Jan Philipp
%A Hadaschik, Boris
%A Schimmöller, Lars
%A Kesch, Claudia
%T Bicenter validation of a risk model for the preoperative prediction of extraprostatic extension of localized prostate cancer combining clinical and multiparametric MRI parameters.
%J World journal of urology
%V 42
%N 1
%@ 0724-4983
%C Heidelberg
%I Springer
%M DKFZ-2024-01897
%P 530
%D 2024
%X This study aimed to validate a previously published risk model (RM) which combines clinical and multiparametric MRI (mpMRI) parameters to predict extraprostatic extension (EPE) of prostate cancer (PC) prior to radical prostatectomy (RP).A previously published RM combining clinical with mpMRI parameters including European Society of Urogenital Radiology (ESUR) classification for EPE was retrospectively evaluated in a cohort of two urological university hospitals in Germany. Consecutive patients (n = 205, January 2015 -June 2021) with available preoperative MRI images, clinical information including PSA, prostate volume, ESUR classification for EPE, histopathological results of MRI-fusion biopsy and RP specimen were included. Validation was performed by receiver operating characteristic analysis and calibration plots. The RM's performance was compared to ESUR criteria.Histopathological T3 stage was detected in 43
%K Humans
%K Male
%K Prostatic Neoplasms: pathology
%K Prostatic Neoplasms: surgery
%K Prostatic Neoplasms: diagnostic imaging
%K Multiparametric Magnetic Resonance Imaging
%K Retrospective Studies
%K Risk Assessment
%K Middle Aged
%K Aged
%K Neoplasm Invasiveness
%K Prostatectomy: methods
%K Predictive Value of Tests
%K Preoperative Care: methods
%K Extraprostatic extension (Other)
%K Multiparametric MRI (Other)
%K Positive surgical margins (Other)
%K Prostate cancer (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39302458
%2 pmc:PMC11415414
%R 10.1007/s00345-024-05232-6
%U https://inrepo02.dkfz.de/record/293574