TY  - JOUR
AU  - Ostau, Nicola Edith von
AU  - Handke, Analena Elisa
AU  - Wiesenfarth, Manuel
AU  - Albers, Peter
AU  - Antoch, Gerald
AU  - Noldus, Joachim
AU  - Reis, Henning
AU  - Cotarelo, Cristina
AU  - Preetz, Julia
AU  - Umutlu, Lale
AU  - Ingenwerth, Marc
AU  - Radtke, Jan Philipp
AU  - Hadaschik, Boris
AU  - Schimmöller, Lars
AU  - Kesch, Claudia
TI  - Bicenter validation of a risk model for the preoperative prediction of extraprostatic extension of localized prostate cancer combining clinical and multiparametric MRI parameters.
JO  - World journal of urology
VL  - 42
IS  - 1
SN  - 0724-4983
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2024-01897
SP  - 530
PY  - 2024
AB  - This study aimed to validate a previously published risk model (RM) which combines clinical and multiparametric MRI (mpMRI) parameters to predict extraprostatic extension (EPE) of prostate cancer (PC) prior to radical prostatectomy (RP).A previously published RM combining clinical with mpMRI parameters including European Society of Urogenital Radiology (ESUR) classification for EPE was retrospectively evaluated in a cohort of two urological university hospitals in Germany. Consecutive patients (n = 205, January 2015 -June 2021) with available preoperative MRI images, clinical information including PSA, prostate volume, ESUR classification for EPE, histopathological results of MRI-fusion biopsy and RP specimen were included. Validation was performed by receiver operating characteristic analysis and calibration plots. The RM's performance was compared to ESUR criteria.Histopathological T3 stage was detected in 43
KW  - Humans
KW  - Male
KW  - Prostatic Neoplasms: pathology
KW  - Prostatic Neoplasms: surgery
KW  - Prostatic Neoplasms: diagnostic imaging
KW  - Multiparametric Magnetic Resonance Imaging
KW  - Retrospective Studies
KW  - Risk Assessment
KW  - Middle Aged
KW  - Aged
KW  - Neoplasm Invasiveness
KW  - Prostatectomy: methods
KW  - Predictive Value of Tests
KW  - Preoperative Care: methods
KW  - Extraprostatic extension (Other)
KW  - Multiparametric MRI (Other)
KW  - Positive surgical margins (Other)
KW  - Prostate cancer (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39302458
C2  - pmc:PMC11415414
DO  - DOI:10.1007/s00345-024-05232-6
UR  - https://inrepo02.dkfz.de/record/293574
ER  -