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@ARTICLE{Doege:293862,
      author       = {D. Doege$^*$ and J. Frick$^*$ and R. Eckford$^*$ and L.
                      Koch-Gallenkamp$^*$ and M. Schlander$^*$ and V. Arndt$^*$},
      collaboration = {B. C. Registry},
      othercontributors = {S. Bergbold and S. Hermann and D. Schuldt},
      title        = {{A}nxiety and depression in cancer patients and survivors
                      in the context of restrictions in contact and oncological
                      care during the {COVID}-19 pandemic.},
      journal      = {International journal of cancer},
      volume       = {156},
      number       = {4},
      issn         = {0020-7136},
      address      = {Bognor Regis},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2024-01992},
      pages        = {711-722},
      year         = {2025},
      note         = {#EA:C070#EA:C071#EA:M110#LA:C070#LA:C071#LA:M110# / 2025
                      Feb 15;156(4):711-722},
      abstract     = {Treatment modifications and contact restrictions were
                      common during the COVID-19 pandemic and can be stressors for
                      mental health. There is a lack of studies assessing
                      pandemic-related risk factors for anxiety and depression of
                      cancer patients and survivors systematically in
                      multifactorial models. A total of 2391 participants, mean
                      age 65.5 years, ≤5 years post-diagnosis of either lung,
                      prostate, breast, colorectal cancer, or leukemia/lymphoma,
                      were recruited in 2021 via the Baden-Württemberg Cancer
                      Registry, Germany. Sociodemographic information,
                      pandemic-related treatment modifications, contact
                      restrictions, and anxiety/depression (Hospital Anxiety and
                      Depression Scale, HADS) were assessed via self-administered
                      questionnaire. Clinical information (diagnosis, stage, and
                      treatment information) was obtained from the cancer
                      registry. Overall, $22\%$ of participants reported
                      oncological care modifications due to COVID-19, mostly in
                      follow-up care and rehabilitation. Modifications of active
                      cancer treatment were reported by $5.8\%.$ Among those,
                      $50.5\%$ had subclinical anxiety and $55.4\%$ subclinical
                      depression (vs. $37.4\%$ and $45.4\%,$ respectively, for
                      unchanged active treatment). Age <60 years, female sex, lung
                      cancer, low income, and contact restrictions to peer support
                      groups or physicians were identified as independent risk
                      factors for anxiety. Risk factors for depression were lung
                      cancer (both sexes), leukemia/lymphoma (females), recurrence
                      or palliative treatment, living alone, low income, and
                      contact restrictions to relatives, physicians, or
                      caregivers. The study demonstrates that changes in active
                      cancer treatment and contact restrictions are associated
                      with impaired mental well-being. The psychological
                      consequences of treatment changes and the importance for
                      cancer patients to maintain regular contact with their
                      physicians should be considered in future responses to
                      threats to public health.},
      keywords     = {SARS‐CoV‐2 (Other) / cancer registry (Other) / mental
                      health (Other) / social contact (Other) / treatment
                      modifications (Other) / well‐being (Other)},
      cin          = {C071 / C100 / M110 / C070},
      ddc          = {610},
      cid          = {I:(DE-He78)C071-20160331 / I:(DE-He78)C100-20160331 /
                      I:(DE-He78)M110-20160331 / I:(DE-He78)C070-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39361297},
      doi          = {10.1002/ijc.35204},
      url          = {https://inrepo02.dkfz.de/record/293862},
}