TY  - JOUR
AU  - Rivas-Delgado, Alfredo
AU  - López, Cristina
AU  - Clot, Guillem
AU  - Nadeu, Ferran
AU  - Grau, Marta
AU  - Frigola, Gerard
AU  - Bosch-Schips, Jan
AU  - Radke, Josefine
AU  - Ishaque, Naveed
AU  - Alcoceba, Miguel
AU  - Tapia, Gustavo
AU  - Luizaga, Luis
AU  - Barcena, Carmen
AU  - Kelleher, Nicholas
AU  - Villamor, Neus
AU  - Baumann, Tycho
AU  - Muntañola, Ana
AU  - Sancho-Cia, Juan M
AU  - García-Sancho, Alejandro M
AU  - Gonzalez-Barca, Eva
AU  - Matutes, Estella
AU  - Brito, Jordi A
AU  - Karube, Kennosuke
AU  - Salaverria, Itziar
AU  - Enjuanes, Anna
AU  - Wiemann, Stefan
AU  - Heppner, Frank L
AU  - Siebert, Reiner
AU  - Climent, Fina
AU  - Campo, Elías
AU  - Giné, Eva
AU  - López-Guillermo, Armando
AU  - Beà, Silvia
TI  - Testicular large B-cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCL.
JO  - HemaSphere
VL  - 8
IS  - 10
SN  - 2572-9241
CY  - [Philadelphia, Pennsylvania]
PB  - Wolters Kluwer Health
M1  - DKFZ-2024-02028
SP  - e70024
PY  - 2024
AB  - Testicular large B-cell lymphoma (TLBCL) is an infrequent and aggressive lymphoma arising in an immune-privileged site and has recently been recognized as a distinct entity from diffuse large B-cell lymphoma (DLBCL). We describe the genetic features of TLBCL and compare them with published series of nodal DLBCL and primary large B-cell lymphomas of the CNS (PCNSL). We collected 61 patients with TLBCL. We performed targeted next-generation sequencing, copy number arrays, and fluorescent in situ hybridization to assess chromosomal rearrangements in 40 cases with available material. Seventy percent of the cases showed localized stages. BCL6 rearrangements were detected in 36
LB  - PUB:(DE-HGF)16
C6  - pmid:39380845
C2  - pmc:PMC11456803
DO  - DOI:10.1002/hem3.70024
UR  - https://inrepo02.dkfz.de/record/293968
ER  -