%0 Journal Article
%A Filippidou, Maria
%A Glentis, Stavros
%A Binenbaum, Ilona
%A Sill, Martin
%A Roka, Kleoniki
%A Vlachou, Antonia
%A Avgerinou, Georgia
%A Ecker, Jonas
%A Selt, Florian
%A Hasselblatt, Martin
%A Blattner-Johnson, Mirjam
%A Schramm, Kathrin
%A Trougkou, Clio
%A Doganis, Dimitrios
%A Katzilakis, Nikolaos
%A Ridola, Vita
%A Papakonstantinou, Evgenia
%A Papadakis, Vassilios
%A Hatzipantelis, Emmanouel
%A Kokkinou, Eleftheria
%A Pons, Roser
%A Kanaka-Gantenbein, Christina
%A Sturm, Dominik
%A Hirsch, Steffen
%A Dikow, Nicola
%A Pajtler, Kristian
%A van Tilburg, Cornelis Martinus
%A Frühwald, Michael C.
%A Milde, Till
%A Witt, Olaf
%A Jones, David
%A von Deimling, Andreas
%A Sahm, Felix
%A Stefanaki, Kalliopi
%A Pfister, Stefan
%A Kattamis, Antonis
%T The impact of methylome analysis on the diagnosis and treatment of CNS tumours in children and adolescents: A population-based study in Greece
%J EJC paediatric oncology
%V 4
%@ 2772-610X
%C [Amsterdam]
%I Elsevier B.V.
%M DKFZ-2024-02087
%P 100198
%D 2024
%Z #EA:B062#LA:B062#
%X Background: The recently published WHO classification of central nervous system (CNS) tumours recognizes DNAmethylation profiling as a desirable and, for some diagnoses, essential diagnostic tool adjunctive to conventionalhistopathology. DNA methylation profiling is not routinely available in many countries, including Greece.Methods: In this collaborative study, we report the DNA methylation results in a series of children and adolescentswith CNS tumours in Greece (2018–2023). In total, 130 tumour samples were analyzed using the latest applicable version of the Heidelberg brain tumour classifier.Results: Upon initial analysis, 80 
%F PUB:(DE-HGF)16
%9 Journal Article
%R 10.1016/j.ejcped.2024.100198
%U https://inrepo02.dkfz.de/record/294066